蔡世仁 醫師 (Shih-Jen Tsai, M. D.) (1961 - ? )

 

1. Christian.

2. One daughter, one son and one dog.

3. Chairman, Department of Psychiatry, Taipei Veteran General Hospital, Taipei, Taiwan.

4. Professor, Psychiatric Division, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

5. Editorial Board of the Journal:

1). Medical Science Monitor

2). Taiwanese Journal of Psychiatry

 

6. Postdoctor Fellow, Psychiatry Department, University of California, San Francisco (2004.7~2005.6)

 

Education: M.D. School of Medicine, National Yang Ming University, Taipei, Taiwan (1979.9~1986.6)

 

Research Topic: Biological Psychiatry (Psychopharmacology; Molecular Psychiatry; Geriatric Psychiatry; Neuroimage).

 

h-index 55 (Google Scholar)

https://scholar.google.com.tw/citations?user=pfWHCtUAAAAJ&hl=zh-TW&oi=ao

 

Refereed Papers: (March 20, 2018) * Corresponding author

 

1.      Hong CJ *, Hsiao KJ, Chen CH, Tsai SJ, Sim CB. Urinary neopterin and biopterin levels in patients with depression. Taiwanese Journal of Psychiatry 1991;5:20-27.

2.      Tsai SJ *, Huang YH, Yu MF, Wang YC, Yang YC, Sim CB. Regional cerebral glucose metabolism in rats after chronic amphetamine administration. Taiwanese Journal of Psychiatry 1994;8(3):150-157.

3.      Tsai SJ *, Huang YH, Chang LS, Yu MF, Yang YC and Sim CB. Alterations in local cerebral glucose utilization in rats after chronic amphetamine administration without subsequent challenge. Psychiatry Research 1995;57(1):65-73.

4.      Huang YH, Tsai SJ *, Chang LS, Yu MF, Yang YC, Sim CB. Metabolic and behavioral response in rats treated with amphetamine chronically with and without challenge. Proceedings of the National Science Council, ROC 1995;19(2):85-91.

5.      Tsai SJ *, Hwang JP, Yang CH, Liu KM. Characteristics of dementia patients with aggressive behaviors. Chang Keng I Hsueh 1995;18(4):305-308.

6.      Tsai SJ *, Hwang JP, Sim CB. Characteristic of elderly patients admitted to the psychiatric ward of a general hospital. Kao Hsiung I Hsueh Ko Hsueh Tsa Chih 1995;11:453-457.

7.      Huang YH, Tsai SJ *, Yu MF, Wang YC, Yang YC, Sim CB. Dose-dependent effects of chronic amphetamine administration in local cerebral glucose utilization in rat. Neuropsychobiology 1995;32(3):149-155.

8.      Huang SC, Tsai SJ *. Hyponatremia and Stevens-Johnson syndrome in a patient receiving carbamazepine. General Hospital Psychiatry 1995;17(6):458-460.

9.      Lu CL, Lee YC, Tsai SJ *, Hu PG, Sim CB. Psychiatric disturbances associated with hyperthyroidism: An analysis report of 30 cases. Chinese Medical Journal 1995;56:143-151.

10.    Tsai SJ, Hwang JP *, Yang CH, Liu KM. Pica phenomena in patients with dementia. Taiwanese Journal of Psychiatry 1995;9(4):95-98.

11.    Yang CH *, Hwang JP, Tsai SJ, Liu KM, Kan YS. Clinical subtypes in psychiatric inpatients with dementia of the Alzheimer's type. Taiwanese Journal of Psychiatry 1995;9(3): 220-226.

12.    Tsai SJ *, Lee YC, Chang K, Sim CB. Psychiatric consultations in pediatric inpatients. Acta Pediatrica Sinica 1995;36(4):411-414.

13.    Hwang JP *, Yang CH, Tsai SJ, Liu KM. Delusions in Alzheimer's disease and vascular dementia. Taiwanese Journal of Psychiatry 1995;9(4):291-298.

14.    Liu KM, Hwang JP *, Tsai SJ, Yang CH, Kan YS. Misidentification in psychiatric inpatient of Alzheimer's disease. Medical Science 1996;17:24-30.

15.    Tsai SJ, Hwang JP *, Yang CH, Liu KM. Physical aggression and associated factors in probable Alzheimer's disease. Alzheimer Disease and Associated Disorders 1996;10(2):82-85.

16.    Lo Y *, Tsai SJ. Trihexyphenidyl abuse in a schizophrenic patient: A case report. Chinese Medical Journal 1996;57:157-160.

17.    Hwang JP *, Yang CH, Tsai SJ, Liu KM. Psychotic symptoms in psychiatric inpatients with dementia of the Alzheimer's and vascular types. Chinese Medical Journal 1996;58(1):35-39.

18.    Lu CL *, Tsai SJ. Hyperthyroidism associated with delirium: 3 case report. Medical Science 1996;17(2):112-117.

19.    Yang CH *, Hwang JP, Tsai SJ, Liu KM, Kan YS. Types and phenomenologic subtypes of dementia in Taiwan: A psychiatric inpatient study. International Journal of Geriatric Psychiatry 1996;11:705-709.

20.    Tsai SJ *, Chang CH, Sim CB. An analysis of the psychiatric inpatients in a medical center. Tzu Chi Medical Journal 1996;8(1):55-60.

21.    Tsai SJ *. Metoclopramide-induced impotence and akathisia: A case report. Chinese Medical Journal 1996;57:443-446.

22.    Tsai SJ, Hwang JP *, Yang CH, Liu KM, Kan YS. Characteristics of dementia patients with hyperphagia. Kao Hsiung I Hsueh Ko Hsueh Tsa Chih 1996;12(3):197-201.

23.    Tsai SJ *, Lee YC, Chang K, Yang CH, Sim CB. Psychiatric consultation in obstetric inpatients. Asia-Oceanic Journal of Obstetrics and Gynecology 1996;22(6):603-607.

24.    Tsai SJ *, Lee YC, Chang K, Sim CB. Psychiatric emergent consultation in a general hospital. Chang Gung Med J 1996;19:337-342.

25.    Lo Y, Tsai SJ *, Chang CH, Hwang JP, Sim CB. Organic delusional disorder in psychiatric inpatients - Comparison with delusional disorder. Acta Psychiatrica Scandinavia 1997;95(2):161-163.

26.    Hwang JP *, Yang CH, Tsai SJ, Liu KM. Delusions of theft in dementia of the Alzheimer's type: A preliminary report. Alzheimer Disease and Associated Disorders 1997;11(2):110-112.

27.    Tsai SJ, Hwang JP *, Yang CH, Liu KM, Lo Y. Capgras' syndrome in a patient with vascular dementia: A Case Report. Kao Hsiung I Hsueh Ko Hsueh Tsa Chih 1997;10(3):639-642.

28.    Hwang JP *, Yang CH, Tsai SJ, Liu KM, Kan YS. Behavioral disturbances in psychiatric inpatients with dementia of the Alzheimer's type in Taiwan. International Journal of Geriatric Psychiatry 1997;12:902-906.

29.    Hwang JP, Tsai SJ *, Yang CH. Geriatric Psychiatry in Taiwan. International Journal of Geriatric Psychiatry 1997;12:960-963.

30.    Huang YH, Tsai SJ *, Yu MF, Wang YC, Yang YC, Sim CB. Differential development of the enhanced metabolic response during amphetamine sensitization. Neuropsychobiology 1997;36:177-181.

31.    Tsai SJ, Hwang JP *, Yang CH, Liu KM. Delusional jealousy in dementia. Journal of Clinical Psychiatry 1997;58:492-494.

32.    Tsai SJ *. Foreign body ingestion in psychiatric inpatients. International Medical Journal 1997;4(4):309-311.

33.    Huang YH *, Tsai SJ, Huang HJ, Sim CB. Effect of repeated D1 or D2 treatment in local cerebral glucose utilization in rat. European Journal of Pharmacology 1997;338:117-121.

34.    Tsai SJ *. Characteristics of elopement in psychiatric ward. International Medical Journal 1998;5(1):63-65.

35.    Huang SC, Tsai SJ *, Chang CH, Hwang JP, Sim CB. Characteristics and outcome of delirium in psychiatric inpatients. Psychiatry and Clinical Neuroscience 1998;52:47-50.

36.    Tsai SJ *, Chang FR. A case of schizophrenia with repetitive hair pulling. British Journal of Dermatology 1998;138(6):1095-1096.

37.    Hwang JP, Tsai SJ *, Yang CH, Liu KM. Hoarding behavior in dementia. American Journal of Geriatric Psychiatry 1998;6:285-289.

38.    Tsai SJ *, Huang YH, Huang HJ, Sim CB. Effects of acute clozapine on local cerebral glucose utilization in the conscious rat. Taiwanese Journal of Psychiatry 1998;12(2):142-149.

39.    Wu TL *, Wu KH, Liu SI, Tsai SJ, Chang K. Psychiatric emergency consultation experience for suicide attempt patients. Taiwanese Journal of Psychiatry 1998;12(2):164-169.

40.    Tsai SJ *, Chen YS. Valproic acid induced Stevens-Johnson syndrome. Journal of Clinical Psychopharmacology 1998;18(5):420.

41.    Hwang JP, Tsai SJ *, Yang CH. Mortality in geriatric psychiatric inpatients. International Journal of Psychiatry in Medicine 1998;28(3):327-331.

42.    Lin CH, Tsai SJ, Yu YWY, Song HL, Tu PC, Sim CB, Hsu CP, Yang KH, Hong CJ *. No evidence for association of serotonin-2A receptor variant (102T/C) with schizophrenia or clozapine response in a Chinese population. Neuroreport 1999;10(1):57-60.

43.    Tsai SJ, Hwang JP *, Yang CH, Liu KM, Lirng JF. Inappropriate sexual behaviors in dementia: a preliminary report. Alzheimer Disease and Associated Disorders 1999;13:60-62.

44.    Tsai SJ *. Cycloid psychosis: a report of two cases. International Medical Journal 1999;6(1):23-25.

45.    Tsai SJ *, Hsiao YH. Secondary personality change in psychiatric inpatients. Psychiatry and Clinical Neuroscience 1999;53(3):433-435.

46.    Chen JY, Hong CJ, Chiu HJ, Lin CY, Bay YM, Song HL, Lai HC, Tsai SJ *. Apolipoprotein E Genotype and Schizophrenia. Neuropsychobiology 1999;39:141-143.

47.    Yu YWY, Tsai SJ, Lin CH, Hsu CP, Yang KH, Hong CJ *. Serotonin-6 receptor variant (C267T) and clinical response to clozapine. Neuroreport 1999;10(6):1231-1233.

48.    Huang YH *, Tsai SJ, Huang HJ, Sim CB. Effect of acute administration of risperidone on local cerebral glucose utilization in rats. European Journal of Pharmacology 1999;370:257-261.

49.    Hong CJ *, Song HL, Lai HC, Tsai SJ, Hsiao KJ. Methanol/Acetone treatment helps the amplification of FMR1 CGG repeat fragment in dried blood spots from Guthrie cards. Lancet 1999;353(9159):1153-1154.

50.    Hwang JP, Tsai SJ *, Yang CH, Liu KM, Lirng JF. Persecutory delusions in dementia. Journal of Clinical Psychiatry 1999;60:550-553.

51.    Wang YC, Liu TY, Liu HC, Chi CW, Sim CB, Tsai SJ, Hong CJ *. No Association between 1-Antichymotrypsin Polymorphism and Alzheimer's Disease in Chinese. Neuropsychobiology 1999;40:67-70.

52.    Chiu HJ, Hong CJ, Chen JY, Wang YC, Lin CY, Bai YM, Song HL, Lai HC, Tsai SJ *. Antichymotrypsin Polymorphism in Schizophrenia: Frequency, Age at Onset, and Cognitive Function. Neuropsychobiology 1999;40:71-74.

53.    Huang YH *, Tsai SJ, Su TW, Sim CB. Effects of repeated high-dose methamphetamine on local cerebral glucose utilization in rats. Neuropsychopharmacology 1999;21:427-434.

54.    Tsai SJ, Hong CJ *, Hsu CC, Cheng CY, Liao WY, Song HL, Lai HC. Serotonin-2A receptor polymorphism (102T/C) in mood disorders. Psychiatry Research 1999;87:233-237.

55.    Tsai SJ *, Chiu HJ, Wang YC, Hong CJ. Association study of Serotonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior. Neuroscience Letter 1999;271:135-137.

56.    Chiu HJ, Tsai SJ, Chen JY, Lin CY, Bai YM, Song HL, Lai HC, Hong CJ *. Variant in presenilin-1 gene and schizophrenia: no association in a Chinese population. Psychiatry Research 1999;87:245-248.

57.    Yang CH, Tsai SJ, Hwang JP *, Liu KM. Wandering and Associated Factors in Dementia of Alzheimer's type: the Clinical Implications for Management. The Journal of Nervous and Mental Disease 1999;187;695-697.

58.    Hong CJ, Tsai SJ *, Cheng CY, Liao WY, Song HL, Lai HC. Association Analysis of the 5-HT6 Receptor Polymorphism (C267T) in Mood Disorders. American Journal of Medical Genetics 1999;88:601-602.

59.    Tsai SJ *, Hong CJ, Wang YC. Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors. Neuroreport 1999;10:3773-3775.

60.    Tsai SJ, Liu HC, Liu TY, Wang YC, Hong CJ *. Association analysis of the 5-HT6 receptor polymorphism C267T in Alzheimer's disease. Neuroscience Letter 1999; 276:138-139.

61.    Hsua JW, Wang YC, Lin CC, Bai YM, Chen JY, Chiu HJ, Tsai SJ, Hong CJ *. No evidence for association of alpha-1a adrenoceptor gene polymorphism and clozapine-induced urinary incontinence. Neuropsychobiology 2000; 42:62-65.

62.    Tsai SJ, Hong CJ *, Yu YWY, Lin CH, Song HL, Lai HC, Yang KH. Association study of a functional serotonin transporter gene polymorphism with schizophrenia, psychopathology and clozapine Response. Schizophrenia Research 2000; 44: 177-181.

63.    Hong CJ, Yu YWY, Lin CH, Song HL, Lai HC, Yang KH, Tsai SJ *. Association study of apolipoprotein E 4 with clinical phenotype and clozapine response in schizophrenia. Neuropsychobiology 2000; 42:172-174.

64.    Tsai SJ *, Wang YC, Hong CJ. Association study of a cannabinoid receptor gene (CNR1) polymorphism with schizophrenia and aggressive behaviors. Psychiatric Genetic 2000;10:149-152.

65.    Lee YC, Chen YS, Yang CH, Tsai SJ *. The correlations between the difficult temperament and the subjective psychiatric symptoms in Chinese early adolescents. Child Psychiatry and Human Development 2000; 31:129-137.

66.    Yang CH, Hwang JP, Tsai SJ *. The clinical applications of Mini-Mental State Examination in geropsychiatric inpatients. International Journal of Psychiatry in Medicine 2000;30:277-285.

67.    Hwang JP, Tsai SJ *, Yang CH, Liu KM, Lirng JF. Repetitive phenomena in dementia. International Journal of Psychiatry in Medicine 2000;30(2):165-171.

68.    Tseng SD *, Tsai SJ. Pregnancy of a female patient treated with olanzapine: A case report. Taiwanese Journal of Psychiatry 2000;14:242-246.

69.    Tsai SJ *, Hong CJ. Haloperidol-induced impotence improved by switching to olanzapine. General Hospital Psychiatry 2000;22:391-392.

70.    Yu YW-Y, Lin CH, Chen SP, Hong CJ, Tsai SJ *. Intelligence and event-related potentials for young female apolipoprotein E e4 and non-e4 carriers. Neuroscience Letter 2000; 294:179-181.

71.    Lam P *, Tsai SJ. Lithium associated hyperparathyroidism: case report. International Medical Journal 2000;7:283-285.

72.    Yu YWY, Tsai SJ, Yang KH, Lin CH, Chen MC, Hong CJ *. Evidence for association between polymorphism in the Serotonin-2a receptor variant (102T/C) and increment of N100 amplitude in schizophrenics treated with clozapine. Neuropsychobiology 2001; 43:79-82.

73.    Wang YC, Tsai SJ, Liu TY, Liu HC, Hong CJ *. No association between tryptophan hydroxylase gene polymorphism and Alzheimer's disease. Neuropsychobiology 2001;43:1-4.

74.    Liou YJ, Tsai SJ *, Hong CJ, Wang YC, Lai IC. Association analysis of a functional catechol-o-methyltransferase gene polymorphism in schizophrenic patients in Taiwan. Neuropsychobiology 2001;43:11-14.

75.    Lai IC, Hong CJ, Tsai SJ *. Association study of nicotinic receptor variant with schizophrenic disorders. Neuropsychobiology 2001;43:15-18.

76.    Hong CJ *, Tsai SJ, Wang YC. Association between tryptophan hydroxylase gene polymorphism (A218C) and schizophrenic disorders. Schizophrenia Research 2001;49:59-63.

77.    Hong CJ, Lin CH, Yu YWY, Yang KH, Tsai SJ *. Genetic variants of the serotonin system, and weight change during clozapine treatment. Pharmacogenetics 2001;11:265-268.

78.    Tsai SJ *, Wang YC, Yu YWY, Lin CH, Yang KH, Hong CJ. Association Analysis of polymorphism in the promoter region of the alpha2a-adrenoceptor gene with schizophrenia and clozapine response. Schizophrenia Research 2001;49:53-58.

79.    Lai IC, Hong CJ, Tsai SJ *. Association study of nicotinic-receptor variants and major depressive disorders. Journal of Affective Disorders 2001;66:79-82.

80.    Lin CH, Hsu CP, Yu YWY, Yang KH, Tsai SJ, Hong CJ *. Anticipation and imprinting in Chinese families with schizophrenia. Psychiatry and Clinical Neurosciences 2001;55:137-140.

81.    Tsai SJ *, Wang YC, Hong CJ. Allelic variants of the alpha 1a adrenoceptor and the promoter region of the alpha 2a adrenoceptor and temperament factors. American Journal of Medical Genetics 2001;105:96-98.

82.    Hong CJ, Wang YC, Liu TY, Liu HC, Tsai SJ *. A study of alpha-adrenoceptor gene polymorphisms and Alzheimer's disease. Journal of Neural Transmission 2001;108:445-450.

83.    Tsai SJ *, Wang YC, Hong CJ. Association study between cannabinoid receptor gene (CNR1) and pathogenesis and psychotic symptoms of mood disorders. American Journal of Medical Genetics 2001;105:219-221.

84.    Tsai SJ *, Huang YH, Huang HJ, Sim CB. Reduced local cerebral glucose utilization in response to long-term clozapine administration in rats. Neuropsychobiology 2001;44:36-40.

85.    Wang YC, Liu HC, Liu TY, Hong CJ, Tsai SJ *. Genetic association analysis of alpha1-antichymotrypsin polymorphism in Parkinson's disease. European Neurology 2001;45:254-256.

86.    Liou YJ, Lai IC, Hong CJ, Liu HC, Liu TY, Tsai SJ *. Association analysis of the partially duplicated alpha7 nicotinic acetylcholine receptor genetic variant and Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 2001;12;301-304.

87.    Tsai SJ, Hong CJ, Liu TY, Cheng CY, Liu HC *. Association study for a functional serotonin transporter gene polymorphism and late-onset Alzheimer's disease for Chinese patients. Neuropsychobiology 2001;44:27-30.

88.    Ouyang WC, Wang YC, Hong CJ, Cheng CY, Tsai SJ*. Association study of angiotensin-converting enzyme (ACE) gene polymorphism with schizophrenia and polydipsia. Neuropsychobiology 2001;44:31-35.

89.    Liu HC *, Hong CJ, Liu CY, Lin KN, Tsai SJ, Liu TY, Chi CW, Wang PN. Association analysis of the 5-HT6 receptor polymorphism C267T with depression in patients with Alzheimer's disease. Psychiatry and Clinical Neurosciences 2001;55:427-429.

90.    Ouyang WC, Wang YC, Hong CJ, Tsai SJ*. Estrogen receptor alpha gene polymorphism in schizophrenia: frequency, age at onset, symptomatology and prognosis. Psychiatric Genetic 2001;11:95-98.

91.    Liao DL, Yeh YC, Chen HM, Chen H, Hong CJ, Tsai SJ*. Association of the Ser9gly polymorphism of the dopamine D3 receptor gene and tardive dyskinesia in Chinese schizophrenia. Neuropsychobiology 2001;44:95-98.

92.    Lin CN, Tsai SJ, Hong CJ*. Association analysis of a functional G protein β3 subunit gene polymorphism (C825T) in mood disorders. Neuropsychobiology 2001;44:118-121.

93.    Yang CH, Tsai SJ, Chang JW, Hwang JP *. Characteristics of Chinese suicide attempters admitted to a geropsychiatric unit. International Journal of Geriatric Psychiatry 2001;16:1033-1036.

94.    Hwang JP, Yang CH, Yu HC, Chang JY, Cheng CY, Tsai SJ *. The efficacy and safety of risperidone for the treatment of geriatric psychosis. Journal of Clinical Psychopharmacology 2001;21:583-587.

95.    Chung MS, Huang SC, Tsai SJ, Chen YS*. Mania associated with electroconvulsive therapy in a patient with obsessive compulsive disorder. International Medical Journal 2001;8:185-186.

96.    Wu WH, Huoa SJ, Cheng CY, Hong CJ, Tsai SJ*. Association study of the 5-HT6 receptor polymorphism (C267T) and symptomatology and antidepressant response in major depressive disorders. Neuropsychobiology 2001;44(4):172-175.

97.    Chiu HJ, Wang YC, Chen JY, Hong CJ, Tsai SJ*. The p53-gene Pro72Arg polymorphism in schizophrenia: Frequency, age at onset, and cognitive function. Psychiatry Research 2001;205:279-283.

98.    Lin CH, Yu YWY, Chen SP, Tsai SJ, Hong CJ *.Association analysis for dopamine D2 receptor Taq1 polymorphism with P300 event-related potential for normal young females. Psychiatric Genetics 2001;11:165-168.

99.    Hong CJ, Yu YWY, Lin CH, Cheng CY, Tsai SJ *. Association analysis of the NMDA receptor subunit 2b (NMDAR2B) genetic variants with psychopathology and clozapine response in schizophrenia. Psychiatric Genetics 2001;11:219-222.

100.  Change HP *, Shih CS, Tsai SJ. Gastroesophageal reflux disease in patients with globus pharyngeus- a preliminary report. J Taiwan Otolaryngol Head Neck Surg 2001;36:334-340.

101.  Tsai SJ, Liu HC, Liu TY, Cheng CY, Hong CJ *.Association analysis for the genetic variants of the NMDA receptor subunit 2b (NR2b) and Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 2002;13:91-94.

102.  Cheng CY, Hong CJ, Liu HC, Liu TY, Tsai SJ*. Association between angiotensin-converting enzyme gene polymorphism and Alzheimer's disease. European Neurology 2002;47:26-29.

103.  Yu HC, Liao KK, Chang TJ, Tsai SJ *. Decrease in prolactin level and increase in P300 amplitude after left prefrontal repetitive transcranial magnetic stimulation (r-TMS) in schizophrenia. American Journal of Psychiatry 2002;159:494-495.

104.  Tsai SJ, Liu HC, Liu TY, Cheng CY, Hong CJ*. Association analysis for the genetic variants of the NMDA receptor 2b subunit (GRIN2B) and Parkinson's disease. Journal of Neural Transmission 2002;109:483-488.

105.  Tsai SJ *, Cheng CY, Shu LRR, Yang CY, Pan CW, Liou YJ, Hong CJ. No association for D2 and D4 dopamine receptor polymorphisms and methamphetamine abuse in Chinese males. Psychiatric Genetics 2002;12:29-33.

106.  Tsai SJ, Yu YWY, Lin CH, Chen TJ, Chen SP, Hong CJ*. Dopamine D2 receptor and N-methyl-D-aspartate receptor 2B subunit genetic variants and intelligence. Neuropsychobiology 2002;45:128-130.

107.  Tsai SJ* ,Ouyang WC, Hong CJ. Association for serotonin transporter gene VNTR polymorphism and schizophrenic disorders. Neuropsychobiology 2002;45:131-133.

108.  Liao DL*, Yang JY, Lee SM, Chen H, Tsai SJ. Smoking in chronic schizophrenic inpatients in Taiwan. Neuropsychobiology 2002;45:172-175.

109.  Tsai SJ*, Wang YC, Hong CJ. Norepinephrine transporter and alpha2c adrenoceptor allelic variants and personality factors. American Journal of Medical Genetics 2002;114: 649-651.

110.  Liou YJ, Hong CJ, Liu HC, Liu CY, Liu TY, Chen IC, Tsai SJ*. Association analysis of the NOS1 gene polymorphism and Alzheimer’s disease. American Journal of Medical Genetics 2002;114:687-688.

111.  Hong CJ *, Lin CH, Yu YWY, Chang SC, Wang SY, Tsai SJ. Genetic variant of the histamine-1 receptor (glu349asp) and body weight change during clozapine treatment. Psychiatric Genetics 2002;12:169-171.

112.  Hong CJ*, Wang YC, Tsai SJ. Association study of angiotensin I-converting enzyme polymorphism and symptomatology and antidepressant response in major depressive disorders. Journal of Neural Transmission 2002;109:1209-1214.

113.  Tsai SJ*, Hong CJ, Cheng CY. Serotonin transporter genetic polymorphisms and harm avoidance in the Chinese. Psychiatric Genetics 2002;12:165-168.

114.  Yu YWY, Tsai SJ, Chen TJ, Lin CH, Hong CJ*. Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders. Molecular Psychiatry 2002;7:1115-1119.

115.  Liao DL, Chen H, Lee SM, Tsai SJ*. Estrogen supplementation for female schizophrenics treated with atypical antipsychotics. Gen Hosp Psychiatry 2002;24:357-359.

116.  Chen TJ, Yu YWY, Chen MC, Tsai SJ, Hong CJ*.Association analysis for serotonin transporter promoter polymorphism and auditory evoked potentials for major depression. Neuropsychobiology 2002;46:57-60.

117.  Lin CN, Liu HC, Tsai SJ, Liu TY, Hong CJ *. Association study for Parkinson's disease and a dopamine transporter gene polymorphism (1215 A/G). Eur Neurology 2002;48:207-209.

118.  Chen TJ, Yu YWY, Chen JY, Wang YC, Chen MC, Hong CJ, Tsai SJ *. Association analysis of two dopamine D2 receptor gene polymorphisms and P300 event-related potential in depressive patients. Neuropsychobiology 2002;46:141-144.

119.  Tsai SJ*, Hong CJ, Yu YWY, Lin CH. Association study of the C-759T genetic variation of the 5-HT2C receptor and clozapine-induced weight gain. Lancet 2002;360:1790.

120.  Hwang SC*, Tsai SJ, Lai TJ. A case report of quetiapine-related tic-like symptoms. Journal of Clinical Psychiatry 2002;63:1184-1185.

121.  Tsai SJ*, Wang YC, Hong CJ, Chiu HJ. Association study of estrogen receptor gene polymorphism and suicidal behaviors in major depressive disorder. Psychiatric Genetics 2003;13(1):19-22.

122.  Tsai SJ*, Yu YWY, Chen TJ, Chen MC, Hong CJ. Association analysis for DRD3, DRD4 and DAT genetic polymorphisms and P300 event-related potentials for normal young females. Psychiatric Genetics 2003;13(1):51-53.

123.  Hwang JP, Yang CH, Lee TW, Tsai SJ *. The efficacy and safety of olanzapine for the treatment of geriatric psychosis. Journal of Clinical Psychopharmacology 2003;23(2):113-118.

124.  Hong CJ, Cheng CY, Shu LRR, Yang CY, Tsai SJ*. Association study of the dopamine and serotonin transporter genetic polymorphisms and methamphetamine abuse in Chinese males. Journal of Neural Transmission 2003;110(4):345-351.

125.  Tsai SJ *, Yu YWY, Chen TJ, Chen JY, Wang YC, Chen MC, Hong CJ. Association study of a functional catechol-O-methyltransferase-gene polymorphism and cognitive function in healthy females. Neuroscience Letter 2003;338(2):123-126.

126.  Tsai SJ *. Attention-deficit hyperactivity disorder and brain-derived neurotrophic factor: a speculative hypothesis. Medical Hypotheses 2003;60:849-851.

127.  Tsai SJ *, Hong CJ. Dopamine receptor hetero-oligomerization: a hypothesis for behavioral sensitization to psychostimulants. Medical Hypotheses 2003;61:18-20.

128.  Tsai SJ *. Brain-derived neurotrophic factor: a bridge between major depression and Alzheimer’s disease? Medical Hypotheses 2003;61:110-113.

129.  Tsai SJ *, Liu HC, Liu TY, Wang KY, Chen MC, Hong CJ. Lack of association between the interleukin-1alpha gene C (-889)T polymorphism and Alzheimer's disease in a Chinese population. Neuroscience Letter 2003;343:93-96.

130.  Hwang TJ, Lee SM, Sun HJ, Lin HN, Tsai SJ, Lee YC, Chen YS*. Amisulpride versus risperidone in the treatment of schizophrenic patients: a double-blind pilot study in Taiwan. J Formos Med Assoc 2003;102:30-36.

131.  Yu YWY, Chen TJ, Wang YC, Liou YJ, Hong CJ, Tsai SJ*. Association analysis for neuronal nitric oxide synthase (nNOS) gene polymorphism with major depression and fluoxetine response. Neuropsychobiology 2003;47:137-140.

132.  Yu YWY, Chen TJ, Hong CJ, Chen HM, Tsai SJ*. Association study of the interleukin-1beta (C-511T) genetic polymorphism with major depressive disorder, associated symptomatology and antidepressant response. Neuropsychopharmacology 2003;28:1182-1185.

133.  Hwang JP, Yang CH, Tsai SJ*. Phantom boarder symptom in dementia. International Journal of Geriatric Psychiatry 2003;18:417-420.

134.  Lee TW, Tsai SJ, Yang CH, Hwang JP*. Clinical and phenomenological comparisons of delusional and non-delusional major depression in the Chinese elderly. International Journal of Geriatric Psychiatry 2003;18:486-490.

135.  Tsai SJ *, Hong CJ. Pharmacogenetics of selective serotonin reuptake inhibitor response in major depression. Current Pharmacogenomics 2003;1:1-7.

136.  Hong CJ *, Tsai SJ. The genomic approach to major depression. Current Pharmacogenomics 2003;1:67-74.

137.  Tsai SJ*, Hong CJ. Dopamine receptor hetero-oligomerization in the pathogenesis of schizophrenia: qualitative as opposed to quantitative notions of dopaminergic receptors. Schizophrenic Research 2003;63:197-198.

138.  Shu LRR, Tsai SJ*. Long-term glue-sniffing: report of six cases. International Journal of Psychiatry in Medicine 2003;33:163-168.

139.  Yen FC, Hong CJ, Huo CJ, Wang JK, Tsai SJ*. Association study of serotonin transporter gene VNTR polymorphism and mood disorders, onset age and suicide attempts in a Chinese sample. Neuropsychobiology 2003;48(1):5-9.

140.  Tsai SJ*, Cheng CY, Yu YWY, Chen TJ, Hong CJ. Association study of a brain-derived neurotrophic-factor genetic polymorphism and major depressive disorders, symptomatology and antidepressant response. American Journal of Medical Genetics 2003;123B:19-22.

141.  Liao DL, Hong CJ, Chen HM, Chen YE, Lee SM, Tsai SJ*. Association of muscarinic M1 receptor genetic polymorphisms with psychiatric symptoms and cognitive function in schizophrenic patients. Neuropsychobiology 2003;48:72-76.

142.  Tsai SJ*, Wang YC, Chen JY, Hong CJ. Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits. Neuropsychobiology 2003;48:68-71.

143.  Hong CJ, Yu YWY, Lin CH, Tsai SJ *. An association study of a BDNF Val66Met polymorphism and clozapine response of schizophrenic patients. Neuroscience Letter 2003;349:206-208.

144.  Hong CJ, Hu WH, Chen CC, Hsiao CC, Tsai SJ*, Ruwe FJL. A double-blind, randomized, fluoxetine-controlled, group-comparative study, comparing the tolerability and efficacy of six weeks treatment with mirtazapine and fluoxetine in Chinese depressed patients. Journal of Clinical Psychiatry 2003;64:921-926.

145.  Tsai SJ *, Hong CJ, Yu YWY, Lin CH, Liu LL. No association of tumor necrosis factor alpha gene polymorphisms with schizophrenia or response to clozapine. Schizophrenia Research 2003;65:27-32.

146.  Liou YJ, Tsai SJ*, Hong CJ, Liao DL. Association analysis for the CA repeat polymorphism of the neuronal nitric oxide synthase (NOS1) gene and schizophrenia. Schizophrenic Research 2003;65:57-59.

147.  Hong CJ, Hou SJ, Yen FC, Tung CL, Pan GM, Tsai SJ *. Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior. Neuropsychobiology 2003;48:186-189.

148.  Lai IC*, Hong CJ, Tsai SJ. The expression of cAMP response element binding protein (CREB) in major depression before and after antidepressant treatment. Neuropsychobiology 2003;48:182-185.

149.  Hong CJ, Liu HC, Liu TY, Lin CH, Cheng CY, Tsai SJ *. Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson's disease and age of onset. Neuroscience Letter 2003;353:75-77.

150.  Lee TW*, Tsai SJ, Hwang JP. Severe cardiovascular side effects of olanzapine in an elderly patient. International Journal of Psychiatry in Medicine 2003;33(4):399-401.

151.  Huang KL, Tsai SJ*. St. John's wort (Hypericum Perforatum) as a treatment for premenstrual dysphoric disorder: a case report. International Journal of Psychiatry in Medicine 2003;33:295-297.

152.  Tsai SJ*, Hong CJ, Yu YWY, Chen TJ. Association study of a brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and personality trait and intelligence in healthy young females. Neuropsychobiology 2004;49:13-16.

153.  Tsai SJ*, Yu YWY, Hong CJ. Personality traits in young female apolipoprotein E (apoE) e4 and non-e4 carriers. American Journal of Medical Genetics 2004;124B:58-60.

154.  Hong CJ, Pan GM, Tsai SJ *. Association study of onset age, attempted suicide, aggressive behavior, and schizophrenia with a serotonin 1B receptor (A-161T) genetic polymorphism. Neuropsychobiology 2004;49:1-4.

155.  Tsai SJ *, Hong CJ, Liu HC, Liu TY, Hsu LE, Lin CH. Association analysis of brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms with Alzheimer’s disease and age of onset. Neuropsychobiology 2004;49:10-12.

156. Tsai SJ*. Is mania caused by overactivity of central brain-derived neurotrophic factor? Medical Hypotheses 2004;62:19-22.

157.  Tsai SJ*. Down-regulation of the Trk-B signal pathway: the possible pathogenesis of major depression. Medical Hypotheses 2004;62:215-218.

158.  Hong CJ, Lai IC, Liou LL, Tsai SJ *. Association study of the human partially duplicated α7 nicotinic acetylcholine receptor genetic variant with bipolar disorder. Neuroscience Letter 2004;355:69-72.

159.  Hwang JP, Yang CH, Tsai SJ*. Comparison study of venlafaxine and paroxetine for the treatment of depression in elderly Chinese inpatients. International Journal of Geriatric Psychiatry 2004;19:189-190.

160.  Huang SC*, Tsai SJ, Chang CC. Fluoxetine-induced memory impairment in four family members. International Journal of Psychiatry in Medicine 2004;34(2):197-200.

161.  Lam P, Cheng CY, Hong CJ, Tsai SJ *. Association study of a brain-derived neurotrophic-factor (Val66Met) genetic polymorphism and panic disorder. Neuropsychobiology 2004;49(4):178-181.

162.  Tsai SJ *, Hong CJ, Liao DL, Lai IC, Liou YJ. Association study of a functional catechol-o-methyltransferase genetic polymorphism with age of onset, cognitive function, symptomatology and prognosis in chronic schizophrenia. Neuropsychobiology 2004;49(4):196-200.

163.  Tsai SJ*, Yu YWY, Lin CH, Wang YC, Chen JY, Hong CJ. Association study of adrenergic b3 receptor (Trp64Arg) and G protein b3 subunit gene (C825T) polymorphisms and weight change during clozapine treatment. Neuropsychobiology 2004;50(1):37-40.

164.  Tsai SJ*, Hong CJ, Yu YWY, Chen TJ. Association study of catechol-O-methyltransferase-gene and dopamine d4 receptor-gene polymorphisms and personality traits in healthy young Chinese females. Neuropsychobiology 2004;50(2):153-156.

165.  Kao CL, Yang YJ, Huang SC*, Tsai SJ. Parenteral zolpidem dependence with opioid-like withdrawal symptoms. J Clin Psychiatry 2004;65(9):1287.

166.  Huang YH*, Cheng CY, Hong CJ, Tsai SJ. Expression of c-Fos-like immunoreactivity in the brain of mice with learned helplessness. Neuroscience Letter 2004;363(3):280-283.

167.  Tsai SJ*. Dopamine receptor down-regulation: an alternative strategy for schizophrenia treatment. Medical Hypotheses 2004;63(6):1047-1050.

168.  Hong CJ, Huo SJ, Liao DL, Lee KL, Wu JY, Tsai SJ*. Case-control and family-based association studies between the neuregulin 1 (Arg38Gln) polymorphism and schizophrenia. Neuroscience Letter 2004;366(2):158-161.

169.  Tsai SJ*, Hong CJ, Yu YWY, Chen TJ, Wang YC, Lin WK. Association study of serotonin 1B receptor (A-161T) genetic polymorphism and suicidal behaviors and response to fluoxetine in major depressive disorder. Neuropsychobiology 2004;50(3):235-238.

170.  Hong CJ, Liao DL, Shih HL, Tsai SJ*. Association study of PICK1 rs3952 polymorphism and schizophrenia. NeuroReport 2004;15(12):1965-1967.

171.  Liu HC, Hong CJ, Liu TY, Chih CW, Tsai SJ*. Association analysis for the muscarinic M1 receptor genetic polymorphisms and Alzheimer’s disease. Dementia and Geriatric Cognitive Disorders 2005 Sep 21;19(1):42-45.

172.  Huo SJ, Yen FC, Cheng CY, Tsai SJ, Hong CJ*. X-box binding protein 1 (XBP1) C-116G polymorphisms in bipolar disorders and age of onset. Neuroscience Letter 2004;367(2):232-234.

173.  Chen TJ, Yu YWY, Hong CJ, Chen MC, Tsai SJ*. Association analysis for C-1019G promoter variant of 5-HT1A receptor gene with auditory evoked potentials in major depression. Neuropsychobiology 2004;50(4):292-295.

174.  Liao DL, Hong CJ, Shih HL, Tsai SJ*. Possible association between serotonin transporter promoter region polymorphism and extremely violent crime in Chinese males. Neuropsychobiology 2004;50(4):284-287.

175.  Yu YWY, Tsai SJ, Hong CJ, Chen TJ*, Yang CW. Association analysis for MAOA gene polymorphism with long-latency auditory evoked potentials in healthy females. Neuropsychobiology 2004;50(4):288-291.

176.  Tsai SJ*. Current aspects of brain-derived neurotrophic factor in psychiatry. Taiwanese Journal of Psychiatry 2004:18:235-50.

177.  Yang CH, Tsai SJ, Hwang JP *. The efficacy and safety of quetiapine for treatment of geriatric psychosis. J Psychopharmacology 2005;19:661-6.

178.  Tsai SJ*. Adenosine A2a receptor/dopamine D2 receptor hetero-oligomerization: a hypothesis that may explain behavioral sensitization to psychostimulants and schizophrenia. Medical Hypotheses 2005;64(1):197-200.

179   Tsai SJ*. Could repetitive transcranial magnetic stimulation (rTMS) be effective in autism? Medical Hypotheses 2005;64:1070-1071.

180.  Cheng CY, Hong CJ, Tsai SJ *. Effects of subchronic clozapine administration on serum glucose, cholesterol and triglyceride levels, and body weight in BALB/c mice. Life Sciences 2005;76:2269-2273.

181.  Lam P, Hong CJ, Tsai SJ *. Association study of A2a adenosine receptor genetic polymorphism in panic disorder. Neuroscience Letters 2005;378:98-101.

182.  Yu YW, Chen TJ, Chen MC, Tsai SJ, Lee TW*. Effect of age and global function score on schizophrenic P300 characteristics. Neuropsychobiology 2005;51:45-52.

183.  Lee TW*, Yu YWY, Chen TJ, Tsai SJ. Loudness dependence of the auditory evoked potential and antidepressant response in Chinese major depressives. Journal of Psychiatry and Neuroscience 2005;30:202-205.

184.  Chen TJ*, Yu YW, Chen MC, Wang SY, Tsai SJ, Lee TW. Serotonin dysfunction and suicide attempts in major depressives: an auditory event-related potential study. Neuropsychobiology 2005;52:28-36.

185. Tsai SJ*. Is autism caused by early hyperactivity of brain-derived neurotrophic factor? Medical Hypotheses 2005;65:79-82.

186.  Tsai SJ *. Strategies to increase central N-acetyl aspartylglutamate: a potential treatment for schizophrenia and bipolar disorders. Schizophrenic Research 2005;76:359-60.

187.  Tsai SJ *, Hong CJ. Pharmacogenetic studies of psychotropic drug-induced adverse effects. Current Pharmacogenomics 2005;3:157-164.

188.  Liu HC, Hong CJ, Liu TY, Tsai SJ *. Association analysis of adenosine A2a receptor 1976T>C polymorphisms with Alzheimer’s disease and its age of onset. European Neurology 2005;53:99-100.

189.  Tsai SJ *, Liao DL, Yu WY, Chen TJ, Wu HC, Lin CH, Cheng CY, Hong CJ. A Study of the Association of (Val66Met) Polymorphism in the brain-derived neurotrophic factor gene with alcohol dependence and extreme violence in Chinese males. Neuroscience Letters 2005;381:340-3.

190.  Tsai SJ*. Asthma, major depression and brain-derived neurotrophic factor. Medical Hypotheses 2005;65:417-8.

191.  Yu WY, Yang CW, Wu HC, Tsai SJ, Hong CJ, Chen MC, Chen TJ*. Association study of a functional MAOA-uVNTR gene polymorphism and personality trait in Chinese young females. Neuropsychobiology 2005;52:118-121.

192.  Tsai CF, Tsai SJ, Hwang JP*. Ziprasidone-induced hypersensitivity syndrome in an aged schizophrenia. International Journal of Geriatric Psychiatry 2005;20:797-799.

193.  Yu WYY, Tsai SJ, Hong CJ, Chen MC, Yang CW, Chen TJ *. Association study of a functional MAOA-uVNTR gene polymorphism and cognitive function in healthy females. Neuropsychobiology 2005;52:77-82.

194.  Tsai SJ*. Possible involvement of brain-derived neurotrophic factor in the antinociceptive effect of antidepressants in neuropathic pain. Medical Hypotheses 2005;65:530-3.

195.  Hong CJ, Liu HC, Liu TY, Liao DL, Tsai SJ *. Association studies of the adenosine A2a receptor (1976T>C) genetic polymorphism in Parkinson's disease and schizophrenia. Journal of Neural Transmission 2005;112:1503-10.

196.  Yu WYY, Tsai SJ, Hong CJ, Chen TJ *, Chen MC, Yang CW. Association study of the monoamine oxidase A gene polymorphism with major depressive disorder and antidepressant response. Neuropsychopharmacology 2005;30:1719-23.

197.  Tsai SJ*. The novel atypical antipsychotic aripiprazole as treatment for and prophylaxis against progressive multifocal leukoencephalopathy. Medical Hypotheses 2005;65:633-4.

198.  Tsai SJ*. Possible involvement of the BDNF-dependent pathway in treatment-emergent suicidality or decreased response to antidepressants. Medical Hypotheses 2005;65:942-6.

199.  Tsai SJ*. Repetitive transcranial magnetic stimulation: a possible novel therapeutic approach to eating disorders. Medical Hypotheses 2005;65:1176-8.

200.  Tsai SJ*. Central N-acetyl aspartylglutamate deficit: a possible pathogenesis of schizophrenia. Medical Science Monitor 2005;11:HY39-45.

201.  Cheng CY, Hong CJ, Yu WYY, Chen TJ, Wu HC, Tsai SJ *. Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with male substance abuse. Molecular Brain Research 2005;140:86-90.

202.  Hong CJ, Yu WYY, Chen TJ, Tsai SJ*. Association study of interleukin-6 genetic polymorphism and major depression. Neuropsychobiology 2005;52:202-205.

203.  Yu WYY*, Tsai SJ, Chen MC, Chen TJ, Yang CW. The relationship between the Tridimensional Personality Traits and loudness dependency of auditory evoked potentials in young females. Taiwanese J Psychiatry 2005;19:110-8.

204.  Hwang JP, Yang CH, Hong CJ, Lirng JF, Yang YM, Tsai SJ*. Association of APOE genetic polymorphism with cognitive function and suicide history in geriatric depression. Dement Geriatr Cogn Disord 2006;22:334-338.

205.  Tsai SJ*, Hong CJ, Liu HC, Liu TY, Liou YJ. The BDNF gene may be a susceptibility candidate for Alzheimer’s disease in a Chinese population. Dementia and Geriatric Cognitive Disord 2006;21:139-143.

206.  Tsai SJ*. The possible role of tissue-type plasminogen activator and the plasminogen system in the pathogenesis of major depression. Medical Hypotheses 2006;66:319-22.

207.  Tsai SJ*, Hong CJ, Hou SJ, Yen FC. Lack of association of catechol-O-methyltransferase gene Val108/158Met polymorphism with schizophrenia: A family-based association study in a Chinese population. Molecular Psychiatry 2006;11:2-3.

208.  Tsai SJ*, Hong CJ, Liao DL, Chang CH. Distribution of androgen receptor CAG repeat polymorphism in Chinese schizophrenia and its correlation with age at onset. Psychoneuroendocrinology 2006;31:270-4.

209.  Tsai SJ*. TrkB partial agonists: potential treatment strategy for epilepsy, mania, and autism. Medical Hypotheses 2006;66:173-5.

210.  Hong CJ, Chen TJ, Yu WYY, Tsai SJ *. Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in major depressive disorder. The Pharmacogenomics Journal 2006;6:27-33.

211.  Tsai SJ*. Deltamethrin, a pyrethroid insecticide, could be a potential antidepressant agent. Medical Hypotheses 2006;66:605-8.

212.  Tsai SJ*. Signal transducer and activator of transcription 6 (STAT6) and attention-deficit hyperactivity disorder: a speculative hypothesis. Medical Hypotheses 2006;67:1342-4.

213.  Hwang JP *, Tsai SJ*, Hong CJ, Yang CH, Lirng JF, Yang YM. The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression. Neurobiol Aging 2006;27:1834-7.

214.  Cheng D, Hong CJ, Liao DL, Tsai SJ *. Association study of androgen receptor CAG repeat polymorphism and male violent criminal activity. Psychoneuroendocrinology 2006;31:548-52.

215.  Tsai SJ *. A clinical view of BDNF-TrkB signaling in the treatment of major depression. Current Signal Transduction Therapy 2007;2:186-189.

216.  Yu WYY, Tsai SJ, Hong CJ, Liou YJ, Chen TJ*. Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders. European Neuropsychopharmacology 2006;16:498-503.

217.  Tsai SJ *, Cheng CY, Hong CJ, Liao DL, Hou SJ, Yen FC, Liou YJ. Association study of polymorphisms in glycine transporter with schizophrenia. Journal of Neural Transmission 2006;113:1545-9.

218.  Tsai SJ *, Hong CJ. Effect of brain derived neurotrophic factor (BDNF) gene variants on therapeutic response and the risk for schizophrenia. Current Pharmacogenomics 2006;4:169-75.

219.  Tsai SJ*. Lithium and antidepressants: potential agents for the treatment of Rett syndrome. Medical Hypotheses 2006;67:626-9.

220.  Hong CJ, Hou SJ, Yen FC, Liou YJ, Tsai SJ*. Family-based association study between the G72/G30 genetic polymorphism and schizophrenia. NeuroReport 2006;17:1067-9.

221.  Tsai SJ*. Cysteamine-related agents could be potential antidepressants through increasing central BDNF levels. Medical Hypotheses 2006;67:1185-8.

222.  Tsai SJ*, Hong CJ, Hou SJ, Yen FC. Association Study of adenosine A2a receptor (1976C>T) genetic polymorphism and mood disorders and age of onset. Psychiatric Genetics 2006;16:185.

223.  Lin CC*, Bai YM, Liu CY, Hsiao MC, Chen JY, Tsai SJ, Ouyang WC, Wu CH, Li YC. Web-based tools can be used reliably to detect patients with major depressive disorder and subsyndromal depressive symptoms. BMC Psychiatry 2007;7:12.

224.  Tsai SJ*. Increased central brain-derived neurotrophic factor activity could be a risk factor for substance abuse: implications for treatment. Medical Hypotheses 2007;68:410-4.

225.  Tsai SJ*. The P11, tPA/plasminogen system and brain-derived neurotrophic factor: implications for the pathogenesis of major depression and the therapeutic mechanism of antidepressants. Medical Hypotheses 2007;68:180-3.

226.  Tsai SJ*. TrkB partial agonists: potential treatment strategy for major depression. Medical Hypotheses 2007;68:674-6.

227.  Tsai SJ*. Attention-deficit hyperactivity disorder may be associated with decreased central brain-derived neurotrophic factor activity: clinical and therapeutic implications. Medical Hypotheses 2007;68:896-9.

228.  Tsai SJ*. Zinc sulfate could be potential agent for the treatment of Rett syndrome through increasing central BDNF levels. Medical Hypotheses 2007;68:230-1.

229.  Tsai SJ*. Semax, an analogue of adrenocorticotropin (4-10), is a potential agent for the treatment of attention-deficit hyperactivity disorder and Rett syndrome. Medical Hypotheses 2007;68:1144-6.

230.  Tsai SJ *, Hong CJ, Cheng CY, Liao DL, Liou YJ. Association study of polymorphisms in post-synaptic density protein 95 (PSD-95) with schizophrenia. Journal of Neural Transmission 2007;114:423-6.

231.  Tsai SJ *. Statins may enhance the proteolytic cleavage of proBDNF: implications for the treatment of depression. Medical Hypotheses 2007;68:1296-9.

232.  Tsai SJ*, Hong CJ, Liou YJ, Liao DL. Association study of GOT2 genetic polymorphisms and schizophrenia. Psychiatric Genetics 2007;17:314.

233.  Tsai SJ*. Glatiramer acetate could be a potential antidepressant through its neuroprotective and anti-inflammatory effects. Med Hypotheses 2007;69:145-8.

234.  Tsai SJ *, Liou YJ, Liao DL, Cheng CY, Hong CJ. No association of GRIP1 gene polymorphisms with schizophrenia in Chinese population. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2007;31:752-5.

235.  Tsai CF, Tsai SJ, Yang CH, Hwang JP*. Chinese demented inpatients admitted following a suicide attempt: a case series. International Journal of Geriatric Psychiatry 2007;22:1106-9.

236.  Tsai SJ *. Glatiramer acetate could be a potential therapeutic agent for Parkinson's disease through its neuroprotective and anti-inflammatory effects. Med Hypotheses 2007;69:1219-21.

237.  Tsai SJ *. Sipatrigine could have therapeutic potential for major depression and bipolar depression through antagonism of the two-pore-domain K+ channel TREK-1. Med Hypotheses 2008;70:548–550.

238.  Hong CJ, Liouc YJ, Liao DL, Hou SJ, Yen FC, Tsai SJ *. Association study of polymorphisms in the mitochondrial aspartate/glutamate carrier SLC25A12 (aralar) gene with schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2007;31:1510-3.

239.  Tsai SJ *, Hong CJ. Effect of brain derived neurotrophic factor (BDNF) gene variants on the therapeutic response and the risk for mood disorders. Current Pharmacogenomics and Personalized Medicine 2008;6:126-133.

240.  Tsai SJ *, Hong CJ, Yu WYY, Chen TJ. Lack of supporting evidence for a genetic association of the FKBP5 polymorphism and response to antidepressant treatment. American Journal of Medical Genetics 2007;144B:1097-1098.

241.  Gau YT, Liou YJ, Yu YWY, Chen TJ, Lin MW, Tsai SJ *, Hong CJ*. Evidence for association between genetic variants of p75 neurotrophin receptor (p75NTR) gene and antidepressant treatment response in Chinese major depressive disorder. American Journal of Medical Genetics 2008;147B(5):594-9.

242.  Tsai SJ *, Liou YJ, Hong CJ, Yu WYY, Chen TJ. Glycogen synthase kinase-3 beta gene is associated with antidepressant treatment response in Chinese major depressive disorder. The Pharmacogenomics Journal 2008;8:384-90.

243.  Li CT, Tsai SJ, Hwang JP *. Pramipexole-induced psychosis in Parkinson's disease: a case report. Psychiatry and Clinical Neurosciences 2008;62:245.

244.  Yang AC*, Tsai SJ, Hong CJ, Hsieh CH, Liu ME, Yang CH. Association of heart rate variability and cognitive functions in nondemented male elderly subjects in the community: a preliminary report. J Am Geriatr Soc 2008;56:958-60.

245.  Tsai SJ *, Gau YT, Liou ME, Hsieh CH, Liou YJ, Hong CJ. Association study of brain-derived neurotrophic factor and apolipoprotein E polymorphisms and cognitive function in aged male without dementia. Neuroscience Letters 2008;433:158-62.

246.  Lin WC, Tsao JH, Tsai SJ *. Delayed thrombocytopenia after valproic acid overdose. General Hospital Psychiatry 2008;30:489-90.

247.  Yeh HL, Tsai SJ *. Lithium may be useful in the prevention of Alzheimer's disease in individuals at risk of presenile familial Alzheimer's disease. Medical Hypotheses. Med Hypotheses 2008;71:948–51.

248.  Liu ME, Hong CJ, Liou YJ, Tsai YL, Hsieh CH, Tsai SJ *. Association study of a functional catechol-O-methyltransferase polymorphism and executive function in elderly males without dementia. Neuroscience Letters 2008;436:193-5.

249.  Tzang RF, Hong CJ, Liou YJ, Yu YWY, Chen TJ, Tsai SJ *. Association study of p11 gene with major depressive disorder, suicidal behaviors and treatment response. Neuroscience Letters 2008;447:92–5.

250.  Tsai SJ *, Hong CJ, Liou YJ, Yu YWY, Chen TJ. Plasminogen activator inhibitor-1 gene is associated with major depression and antidepressant treatment response. Pharmacogenetics and Genomics 2008;18:869-875.

251.  Gau YT, Hong CJ, Tsai SJ *. Can antidepressants act as potential pro-neoplastic agents in patients with neurotrophic factor-related cancers? CNS Spectrums 2008;13:849-50.

252.  Shieh CH, Hong CJ, Huang YH, Tsai SJ *. Potential antidepressant properties of cysteamine on hippocampal BDNF levels and behavioral despair in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2008;32:1590-4.

253.  Wang YC, Chen JY, Chen ML, Chen CH, Lai IC, Chen TT, Hong CJ, Tsai SJ, Liou YJ*. Neuregulin 3 (NRG3) genetic variations and susceptibility to schizophrenia in a Chinese population. Biol Psychiatry 2008;64:1093-6.

254.  Tsai SJ *, Hong CJ, Liou YJ. Brain-derived neurotrophic factor and antidepressant action: another piece of evidence from pharmacogenetics. Pharmacogenetics 2008;9:1353-8.

255.  Tsai SJ *, Gau YT, Hong CJ, Liou YJ, Yu YWY, Chen TJ.Sexually dimorphic effect of catechol-O-methyltransferase Val158Met polymorphism on clinical response to fluoxetine in major depressive patients. Journal of Affective Disorders 2009;113:183-7.

256.  Hou SJ, Yen FC, Tsai SJ *. Is dysfunction of the tissue plasminogen activator (tPA)-plasmin pathway a link between major depression and cardiovascular disease? Med Hypotheses 2009;72:166-8.

257. Chang HC, Tang CH, Tsai SJ, Yen FC, Su KP*. Long-acting injectable risperidone and hospital readmission: A mirror image study with a national claim-based database in Taiwan. J Clin Psychiatry 2009;70:141.

258.  Hwang JP*, Tsai SJ, Yang CH, Hsu CD, Hong CJ. Interleukin-1 beta 2511C/T genetic polymorphism is associated with age of onset of geriatric depression. NeuroMolecular Medicine 2009;11:322-7.

259.  Tsai SJ *, Hong CJ, Liou YJ, Chen TJ, Chen ML, Hou SJ, Yen FC, Yu YWY. Haplotype analysis of single nucleotide polymorphisms in the vascular endothelial growth factor (VEGFA) gene and antidepressant treatment response in major depressive disorder. Psychiatry Research 2009;169:113-7.

260.  Tsai SJ *. Statins may act through increasing tissue plasminogen activator/plasmin activity to lower risk of Alzheimer's disease. CNS Spectrums 2009;14:234-235.

261.  Su KP, Chang HC, Tsai SJ, Tang CH*. Relapse and long-acting injectable risperidone: A one-year mirror image study with a national claims database in Taiwan. Value in Health 2009;12:S118 - S121.

262.  Tsai SJ *, Hong CJ, Liou YJ, Yu YWY, Chen TJ, Hou SJ, Yen FC. Tryptophan hydroxylase 2 gene is associated with major depression and antidepressant treatment response. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2009;33:637-41.

263.  LiouYJ, Chen TJ, Tsai SJ, Yu YWY, Cheng CY, Hong CJ*. Support for the involvement of the KCNK2 gene in major depressive disorder and response to antidepressant treatment. Pharmacogenetics and Genomics 2009;19:735-41.

264.  Lin E, Hong CJ, Hwang JP, Liou YJ, Yang CH, Cheng D, Tsai SJ *. Gene-gene interactions of the brain-derived neurotrophic factor and neurotrophic tyrosine kinase receptor 2 genes in geriatric depression. Rejuvenation Research 2009;12:387-93.

265.  Liu ME, Tsai SJ, Yang ST*. Varenicline-induced mixed mood and psychotic episode in a patient with schizoaffective disorder. CNS Spectrums 2009;14:346.

266.  Huang SC, Tsai SJ *, Yang HJ. Aripiprazole improves social interaction in Taiwanese children with pervasive developmental disorder. Chang Keng I Hsueh 2010;33:211-5.

267.  Tsai SJ *, Hong CJ, Liu ME, Hou SJ, Yen FC, Hsieh CH, Liou YJ. Interleukin-1 beta (C-511T) genetic polymorphism is associated with cognitive performance in elderly males without dementia. Neurobiology of Aging 2010;31:1950-5.

268.  Tsai CF*, Ouyang WC, Tsai SJ, Hong CJ, Lin TL. Risk factors for poor sleep quality among patients with interstitial cystitis in Taiwan. Neurourology and Urodynamics 2010;29:568-72.

269.  Lee YT, Tsai SJ *. The mirror neuron system may play a role in the pathogenesis of mass hysteria. Med Hypotheses 2010;74:244–245.

270.  Fukumoto N, Fujii T, Combarros O, Kamboh MI, Tsai SJ, Matsushita S, Nacnias B, Comings DE, Arboleda H, Ingelsson M, Hyman BT, Akatsu H, GrupeA, Nishimura AL, Zatz M, Mattila KM, GotoY, Asada T, Nakamura S, Kunugi H*. Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer’s disease: new data and meta-analysis. American Journal of Medical Genetics 2010;153B:235-42.

271.  Cheng D, Tsai SJ, Hong CJ, Yang AC*. Reduced physiological complexity in robust elderly adults with the APOE ε4 allele. PLoS ONE 2009; 3(11): e7733.

272.  Yang SY, Hong CJ, Huang YH, Tsai SJ*. The effects of glycine transporter I inhibitor, N-methylglycine (sarcosine), on ketamine-induced alterations in sensorimotor gating and regional brain c-Fos expression in rats. Neuroscience Letters 2010;469:127–130.

273.  Yang AC*, Chen TJ, Tsai SJ, Hong CJ, Kuo CH, Yang CH, Kao KP. BDNF Val66Met polymorphism alters sympathovagal balance in healthy subjects. Am J Med Genet B Neuropsychiatr Genet 2010;153B:1024-30.

274.  Hsu CD, Tsai SJ*. The tissue plasminogen activator/plasmin system may act through the cleavage of proBDNF to increase risk of substance abuse. CNS Spectrums 2010;15:350.

275.  Hwang JP*, Lee TW, Tsai SJ, Chen TJ, Yang CH, Lirng JF, Tsai CF. Cortical and subcortical abnormalities in late-onset depression with history of suicide attempts investigated with MRI and voxel-based morphometry. Journal of Geriatric Psychiatry and Neurology 2010;23:171-84.

276.  Lin PY, Hong CJ, Tsai SJ*. Serotonin syndrome caused by ziprasidone alone. Psychiatry and Clinical Neurosciences 2010;64:338-9.

277.  Yang AC*, Hong CJ, Kuo CH, Chen TJ, Yang CH, Li C, Tsai SJ. Profiling objective sleep quality in a healthy Taiwanese sample using a novel electrocardiogram-based cardiopulmonary coupling analysis. Taiwanese Journal of Psychiatry 2010;24:191-200.

278.  Yang AC, Hong CJ, Tsai SJ*. Heart rate variability in psychiatric disorders. Taiwanese Journal of Psychiatry 2010;24:99-109.

279.  Hwang SJ*, Tsai SJ, Chen IJ, Hsu FC, Li C, Kao KP. Choking Incidents Among Psychiatric Inpatients: A Retrospective Study in Chutung Veterans General Hospital. J Chin Med Assoc 2010;73: 419-424.

280.  Hong CJ, Liou YJ, Bai YM, Chen TT, Wang YC, Tsai SJ*. Dopamine receptor D2 (DRD2) gene is associated with weight gain in schizophrenic patients under long-term atypical antipsychotic treatment. Pharmacogenetics and Genomics 2010;20:359-66.

281.  Luo KR, Hong CJ, Liou YJ, Hou SJ, Huang YH*, Tsai SJ*. Differential regulation of neurotrophin S100B and BDNF in two rat models of depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2010;34:1433-9.

282.  Yang AC*, Huang NE, Peng CK, Tsai SJ*. Do seasons have an influence on the incidence of depression? The use of an internet search engine query data as a proxy of human affect. PLoS ONE 2010;5:e13728.

283.  Yang AC*, Hwang JP, Tsai SJ, Yeh HL, Chen JY, Liou YJ, Hwang JP, Hong CJ. Association of renal function and cognitive performance in elderly community-dwelling men without dementia. Journal of the American Geriatrics Society 2010;58:2046-7.

284. Hong CJ, Tsai PJ, Cheng CY, Chou CK, Jheng HF, Chuang YC, Yang CN, Lin YT, Hsu CW, Cheng IH, Chen SY, Tsai SJ, Liou YJ, Tsai YS*. ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin. PLoS ONE 2010;5:e15333.

285.  Tsai SJ*, Hong CJ, Liou YJ. Effects of brain-derived neurotrophic factor (BDNF) polymorphisms on antidepressant action. (review) Psychiatry Investigation 2010;7:236-42.

286. Tsai YL, Tsai SJ, Huang JP, Liu ME. Godot Syndrome in an Elderly Patient with Pseudodementia. Taiwanese Journal of Psychiatry 2010;24:78-80.

287.  Lee CY*, Tsai SJ. Detoxification with intravenous drip short-acting benzodiazepines in a zolpidem-dependent patient with intolerable withdrawal dizziness. Taiwanese Journal of Psychiatry 2011;25:41-4.

288.  Yang AC*, Tsai SJ, Huang NE. Decomposing the association of completed suicide with air pollution, weather, and unemployment data at different time scales. Journal of Affective Disorders 2011;129:275-81..

289.  Yang AC*, Yang CH, Hong CJ, Tsai SJ, Kuo CH, Peng CK, Mietus JE, Goldberger AL, Thomas RJ. Sleep state instabilities in major depression: detection and quantification with an electrocardiogram-based cardio-pulmonary coupling analysis. Psychophysiology 2011;48:285-291.

290.  Liou YJ, Chen TJ, Tsai SJ, Yu YWY, Chen SY, Hong CJ*. Evidence of involvement of the human Par-4 (PAWR) gene in major depressive disorder. The World Journal of Biological Psychiatry 2011;12:288-95.

291.  Lee TW, Yu YWY, Hong CJ, Tsai SJ, Wu HC, Chen TJ*. The influence of serotonin transporter polymorphisms on cortical activity: A resting EEG study. BMC Neuroscience 2011;12:33.

292.  Tsai SJ*, Hong CJ, Liou YJ. Recent molecular genetic studies and methodological issues in suicide research. (review) Progress in Neuro-Psychopharmacology & Biological Psychiatry 2011;35:809–817.

293.  Yang AC*, Tsai SJ*, Hong CJ, Wang C, Chen TJ, Liou YJ, Peng CK. Clustering heart rate dynamics is associated with beta-adrenergic receptor polymorphisms: analysis by information-based similarity index. PLoS ONE 2011;6:e19232.

294.  Bai YM, Chen TT, Liou YJ, Hong CJ, Tsai SJ*. Association between HTR2C polymorphisms and metabolic syndrome in schizophrenic patients treated with atypical antipsychotics. Schizophrenia Research 2011;125:179–186.

295.  Lee TW, Yu YWY, Hong CJ, Tsai SJ, Wu HC, Chen TJ*. The effects of catechol-O-methyl-transferase polymorphism Val158Met on functional connectivity in healthy young females: a resting EEG study. Brain Research 2011;1377:21-31.

296.  Yang AC*, Tsai SJ, Huang NE, Peng CK. Association of Internet search trends with suicide death in Taipei city, Taiwan, 2004-2009. Journal of Affective Disorders 2011;132(1-2):179-84.

297.  Chen SP, Fuh JL, Wang SJ*, Tsai SJ, Hong CJ, Yang AC. Brain-derived neurotrophic factor gene Val66Met polymorphism modulates reversible cerebral vasoconstriction syndromes. PLoS ONE 2011;6(3): e18024.

298.  Ozdemir V, Muljono DH, Pang T, Ferguson LR, Manamperi A, Samper S, Someya T, Tasse AM, Tsai SJ, Zhou HH, Lee EJD. Asia-Pacific Health 2020 and Genomics without Borders: Co-Production of Knowledge by Science and Society Partnership for Global Personalized Medicine. Current Pharmacogenomics and Personalized Medicine 2011;9:1-5.

299.  Huang HH, Wang YJ, Wu CL, Hong CJ, Bai YM, Tsai SJ, Liou YJ. TNF-α -308 G>A polymorphism and weight gain in patients with schizophrenia under long-term clozapine, risperidone or olanzapine treatment. Neuroscience Letters 2011;504:277-80.

300.  Tsai A, Liou YJ, Hong CJ, Wu CL, Tsai SJ*, Bai YM*. Association study of brain-derived neurotrophic factor gene polymorphisms and body weight change in schizophrenic patients under long-term atypical antipsychotic treatment. Neuromolecular Med 2011;13:328-33.

301.  Liu ME, Tsai SJ, Jeang SY, Peng SL, Wu SL, Chen MC, Tsai YL, Yang ST*. Varenicline prevents affective and cognitive exacerbation during smoking abstinence in male patients with schizophrenia. Psychiatry Res 2011;190:79-84.

302.  Lin E, Tsai SJ*. Gene-gene interactions in a context of individual variability in antipsychotic drug pharmacogenomics. (review) Curr Pharmacogenomics Person Med 2011; 9(4):323-331.

303.  Liu ME, Tsai SJ, Lu T, Hong CJ, Chen MC, Lin SL, Yeh HL, Ku YC. No association of angiotensin I converting enzyme I/D polymorphism with domain-specific cognitive function in aged men without dementia. Neuromolecular Med 2011;13:212-6.

304.  Hong CJ, Liou YJ, Tsai SJ*. Effects of BDNF polymorphisms on brain function and behavior in health and disease. (review) Brain Research Bulletin 2011;86:287-97.

305.  Yeh HL, Hou SJ, Yen FC, Hong CJ, Liou YJ, Yang AC, Liu ME, Tsai SJ*. Polymorphisms in LMNA and near a SERPINA13 gene are not associated with cognitive performance in Chinese elderly males without dementia. Neuroscience Letters 2011;504:32-4.

306. Tsai SJ*, Hong CJ, Yeh HL, Liou YJ, Yang AC, Liu ME, Hwang JP*. Heterozygote advantage of the MTHFR C677T polymorphism on specific cognitive performance in elderly Chinese males without dementia. Dementia and Geriatric Cognitive Disorders 2011;32:159-163.

307. Chen HC, Tsai SJ*. Trazodone-induced severe headache. Psychiatry and Clinical Neurosciences 2011;65(7):681-2.

308.  Yang AC*, Tsai SJ, Yeh HL, Yang CH, Kuo CH, Chen TJ, Hong CJ*. Reduced physiologic complexity is associated with poor sleep in patients with major depression and primary insomnia. Journal of Affective Disorders 2011;131:179-85.

309.  Liou YJ, Bai YM, Lin E, Chen JY, Chen TT, Hong CJ*, Tsai SJ*. Gene-gene interactions of the INSIG1 and INSIG2 in metabolic syndrome in schizophrenic patients treated with atypical antipsychotics. The Pharmacogenomics Journal 2012;12(1):54-61.

310.  Hong CJ*, Chen TT, Bai YM, Liou YJ, Tsai SJ*. Impact of Apolipoprotein A5 (APOA5) polymorphisms on serum triglyceride levels in schizophrenic patients under long-term atypical antipsychotic treatment. The World Journal of Biological Psychiatry 2012;13(1):22-9.

311.  Pan CH, Tsai SJ*. Early intervention with psychostimulants or antidepressants to increase methyl-CpG-binding protein 2 (MeCP2) expressions: a potential therapy for Rett syndrome. Med Sci Monit 2012;18(1):HY1-3.

312.  Chen HH, Heh HL, Tsai SJ*. Association of lower hemoglobin levels with depression, though not with cognitive performance, in healthy elderly males. Psychiatry and Clinical Neurosciences 2012;66(4):367-9.

313.  Liou YJ, Chen CH, Cheng CY, Chen SY, Chen TJ, Yu YWY, Nian FS, Tsai SJ, Hong CJ *. Convergent evidence from mouse and human studies suggests the involvement of Zinc Finger Protein 326 gene in antidepressant treatment response. PLoS ONE 2012;7(5):e32984.

314. Huang HH, Hong CJ, Yeh HL, Liou YJ, Yang AC, Liu ME, Tsai SJ*. Dopamine D2 receptor gene Taq1 A polymorphism is associated with cognitive performance in elderly males without dementia. Taiwanese Journal of Psychiatry 2012; 26:32-40.

315.  Hsu CD, Tzang RF, Loh EW, Liou YJ, Hong CJ, Tsai SJ*. Family-based association study of cocaine- and amphetamine-regulated transcript (CARTPT) and protein interaction with C-kinase-1 (PICK1) genes in attention-deficit hyperactivity disorder. Psychiatry Research 2012;198:334-5.

316.  Tsai SJ*. Peripheral administration of brain-derived neurotrophic factor to Rett syndrome animal model: a possible approach for the treatment of Rett syndrome. Med Sci Monit 2012;18(8):HY33-36.

317.  Liou YJ, Wang HH, Lee MM, Wang SC, Chiang HL, Chen CC, Lin CH, Chung MS, Kuo CC, Liao DL, Wu CK, Liu CM, Liu YL, Hwu HG, Lai IC, Tsai SJ, Chen CH, Liu HF, Chou YC, Chen CH, Chen YT, Hong CJ*, Yu JY*. Genome-wide association study of treatment refractory schizophrenia in Han Chinese. PLoS ONE 2012;7(3):e33598.

318.  Lee TW, Yu YW, Hong CJ, Tsai SJ, Wu HC, Chen TJ*. The influence of dopamine receptor D4 polymorphism on resting EEG in healthy young females. Open Neuroimag J 2012;6:19-25.

319.  Lee TW, Yu YW, Hong CJ, Tsai SJ, Wu HC, Chen TJ*. The Influence of Apolipoprotein E Epsilon4 Polymorphism on qEEG Profiles in Healthy Young Females: A Resting EEG Study. Brain Topogr 2012;25(4):431-42.

320.  Yang AC, Huang CC, Yeh HL, Liu ME, Hong CJ, Tu PC, Chen JF, Huang N, Peng CK, Lin CP*, Tsai SJ*. Complexity of spontaneous BOLD activity in default mode network is correlated to cognitive function in normal male elderly: a multiscale entropy analysis. Neurobiology of Aging 2013;34:428-438.

321.  Lan WH , Yang AC, Hwang JP, Hong CJ, Liou YJ, Yeh HL, Liu ME, Tsai SJ*. Association of MTHFR C677T polymorphism with loneliness but not depression in cognitively normal elderly males. Neuroscience Letters 2012;521(1):88-91.

322.  Hsu CD, Tzang RF, Liou YJ, Hong CJ, Tsai SJ*. Family-based association study of tryptophan hydroxylase-2 and serotonin 1A receptor genes in attention-deficit hyperactivity disorder. Psychiatric Genetics 2013 Feb;23(1):38.

323.  Liu ME, Huang CC, Hwang JP, Yang AC, Tu PC, Yeh HL, Hong CJ, Liou YJ, Chen JF, Lin CP*, Tsai SJ*. Effect of Bcl-2 rs956572 SNP on regional gray matter volumes and cognitive function in elderly males without dementia. Age 2013;35(2):343-52.

324.  Lin E*, Tsai SJ. Novel Diagnostics R&D for Public Health and Personalized Medicine in Taiwan: Current State, Challenges and Opportunities". Curr Pharmacogenomics Person Med 2012;10(3):239-246.

325.  Tsai SJ*, Yeh HL, Hong CJ, Liou YJ, Yang AC, Liu ME, Hwang JP*. Association of CHRNA4 polymorphism with depression and loneliness in elderly males. Genes, Brain and Behavior 2012;11:230–234.

326.  Shen CC, Tsai SJ, Perng CL, Kuo BI, Yang AC*. Risk of Parkinson disease following depression: A nationwide population-based study. Neurology 2013;81(17):1538-44.

327.  Lee TW, Yu YWY, Hong CJ, Tsai SJ, Chen MC, Chen TJ. The influence of NMDA receptor 2B subunit (GRIN2B) on cortical electrical oscillation. World Journal of Neuroscience 2011;1:38-44.

328.  YangAC*, Yang CH, Hong CJ, Liou YJ, Shia BC, Peng CK, Huang NE, Tsai SJ. Effect of age, sex, index admission, and predominant polarity on the seasonality of acute admissions for bipolar disorder: a population-based study. Chronobiology International 2013;30(4):478-85.

329.  Huang KL, Tsai SJ*. The importance of measuring impulsiveness in patients with addiction problems. J Chin Med Assoc 2013;76:241-2.

330.  Ku YC*, Liu ME, Tsai YF, Liu WC, Lin SL, Tsai SJ*. Associated factors for falls, recurrent falls, and injurious falls in aged men living in Taiwan Veterans Homes. International Journal of Gerontology 2013;7:80–84.

331.  YangAC*, Tsai SJ. Is Mental illness complex? From behavior to brain. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2013;45:253-7.

332.  Liou YJ, Tsai SJ, Wang YJ, Bai YM*, Hong CJ. Genetic Variants of Microsomal Triglyceride Transfer Protein (MTTP) Are Associated With Metabolic Syndrome in Schizophrenic Patients Treated With Atypical Antipsychotics. The Journal of Clinical Psychopharmacology 2013;33(3):313-8.

333.  Guan CH, Tsai SJ*. Paliperidone in the treatment of Tourette syndrome with comrobid schizophrenia. Psychiatry Clin Neurosci 2013;67:128.

334.  Tsai SJ*. Decreased synthesis of brain-derived neurotrophic factors in vascular endothelial cells of clinically depressed patients: implications for depression pathogenesis and treatment. Hypotheses in the Life Sciences 2012;2:60-3.

335.  Tsai A, Huang CC, Yang AC, Liu ME, Tu PC, Hong CJ, Liou YJ, Chen JF, Lin CP, Tsai SJ*. Association of BACE1 gene polymorphism with cerebellar volume but not cognitive function in normal individuals. Dementia and Geriatric Cognitive Disorders EXTRA 2012;2:632–637.

336.  Ko FY, Tsai SJ, Yang AC, Zhou Y, Xu LM*. Association of CD8 T cells with depression and anxiety in patients with liver cirrhosis. International Journal of Psychiatry and Medicine 2013;45:15-29.

337.  Tsai SJ*. Recent molecular genetic studies and methodological issues in major dpression rsearch. Taiwanese Journal of Psychiatry 2013;27(1):11-21.

338.  Liu ME, Huang CC, Yang AC, Tu PC, Yeh HL, Hong CJ, Chen JF, Liou YJ, Lin CP*, Tsai SJ*. Effect of Bcl-2 rs956572 polymorphism on age-related gray matter volume changes. PLOS ONE 2013;8(2):e56663.

339.  Ko FY, Yang AC, Tsai SJ, Zhou Y, Xu LM*. Physiologic and laboratory correlates of depression, anxiety, and poor sleep in liver cirrhosis. BMC Gastroenterology 2013 Jan 22;13(1):18.

340.  Chou YH*, Chen CK, Wang SJ, Tsai SJ, Lirng JF, Liou YJ, Lin CL, Yang KC, Lin MW, Lo WC, Liao MH, Chen CC. Association of Brain Serotonin Transporter Availability and Brain-Derived Neurotrophic Factor in Models of Serotonin Transporter Genotypes in Healthy Subjects. Journal of Clinical Psychopharmacology 2013;33(3):432-435.

341.  Liu ME, Tsai SJ, Chang WC, Hsu CH, Lu T, Hung KS, Chiu WT, Chang WP*. Population-based 5-year follow-up study in Taiwan of dementia and risk of stroke. PLOS ONE 2013;8(4):e61771.

342.  Di X, Kim EH, Huang CC, Tsai SJ, Lin CP, Biswal BB. The influence of the amplitude of low-frequency fluctuations on resting-state functional connectivity. Front Hum Neurosci 2013;7:118.

343.  Tzang RF, Hsu CD, Liou YJ, Hong CJ, Tsai SJ*. Family-based association of the brain-derived neurotrophic factor gene in attention-deficit hyperactivity disorder. Psychiatr Genet 2013;23(4):177-8.

344.  YangAC*, Tsai SJ, Yang CH, Shia BC, Fuh JL, Wang SJ, Peng CK, Huang NE. Suicide and media reporting: a longitudinal and spatial analysis. Social Psychiatry and Psychiatric Epidemiology 2013;48(3):427-35.

345.  Tu PC, Su T, Huang A, Yang AC, Yeh HL, Hong CJ, Liou YJ, Liu ME, Lin CP*, Tsai SJ*. Interleukin-1 beta C-511T polymorphism modulates cortico-striatal functional connectivity within the cingulo-opercular network in non-demented Elderly Han Males. Brain Structure & Function 2014;219(1):61-9.

346.  Wang TY, Tsai SJ*. Risperidone and quetiapine-related arthralgia. Journal of Clinical Psychopharmacology 2014;34(2):271-2.

347. Yang AC, Huang CC, Liu ME, Liou YJ, Hong CJ, Lo MT, Huang N, Peng CK, Lin CP*, Tsai SJ*. The APOE ε4 allele affects complexity and functional connectivity of resting brain activity in healthy adults. Human Brain Mapping 2014;35(7):3238-48.

348. Liu ME, Huang CC, Chen MH, Yang AC, Tu PC, Yeh HL, Hong CJ, Chen JF, Hwang JP, Lin CP*, Tsai SJ*. Effect of the BDNF Val66Met Polymorphism on Regional Gray Matter Volumes and Cognitive Function in the Chinese Population. NeuroMolecular Medicine 2014;16(1):127-36.

349.  Chang WP, Liu ME, Chang WC, Yang AC, Ku YC, Pai JT, Tsai SJ*. Sleep Apnea and the Risk of Dementia: A Population-based 5-year Follow-up Study in Taiwan. PLOS ONE 2013;8(10):e78655.

350.  Huang CC, Liu ME, Chou KH, Yang AC, Hung CC, Hong CJ, Tsai SJ*, Lin CP*. Effect of BDNF Val66Met Polymorphism on Regional Gray Matter Volumes and Cognitive Function in the Chinese Population. Psychoneuroendocrinology 2014;39:94-103.

351.  Wang HH, Hong CJ, Yeh HL, Liou YJ, Yang AC Liu ME, Tsai SJ*.  Interleukin-1 alpha (rs1800587) genetic polymorphism is associated with specific cognitive functions but not depression or loneliness in elderly males without dementia. Neuroscience Letters 2013;556:69-72.

352.  Liou YJ, Chen TJ, Cheng CY, Yu YWY, Hong CJ, Tsai SJ*. Brain-derived Neurotrophic Factor Genetic Variants are Associated with Major Depression Susceptibility and Antidepressant Treatment Response. Current Pharmacogenomics and Personalized Medicine 2013;11:316-323.

353.  Liu ME, Huang CC, Yang AC, Tu PC, Yeh HL, Hong CJ, Liou YJ, Chen JF, Chou KH, Lin CP*, Tsai SJ*. Catechol-O-Methyltransferase Val158Met Polymorphism on the Relationship between White Matter Hyperintensity and Cognition in Healthy People. PLOS ONE 2014;9(2):e88749.

354.  Tzang RF, Hsu CD, Liou YJ, Hong CJ, Tsai SJ*. Family-based association study of ciliary neurotrophic factor receptor (CNTFR) and norepinephrine transporter (NET) genes in attention-deficit hyperactivity disorder. Psychiatric Genetics 2014;24(3):118-9.

355.  Chang PT, Tsai SJ*. Myalgia induced by antidepressants. The Journal of Neuropsychiatry and Clinical Neurosciences 2014;26(3):E12.

356.  Chou PS, Chou WP, Chou YH, Liu ME, Lai CL, Liu CK, KuYC, Tsai SJ, Chang WC, Chang WP. Increased Risk of Benign Prostate Hyperplasia in Sleep Apnea Patients: A Nationwide Population-Based Study. PLOS ONE 2014 Mar 25;9(3):e93081.

357.  Hung JH, Hu LY, Tsai SJ, Yang AC, Huang MW, Chen PM, Wang SL, Lu T, Shen CC. Risk of Psychiatric Disorders following Polycystic Ovary Syndrome: A Nationwide Population-Based Cohort Study. PLOS ONE 2014;9(5):e97041.

358.  Li CT, Chen MH, Juan CH, Huang HH, Chen LF, Hsieh JC, Tu PC, Bai YM, Tsai SJ, Lee YC, Su TP. Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study. Brain 2014;137(Pt 7):2088-98.

359.  Bai YM, Su TP, Li CT, Tsai SJ, Chen MH, Tu PC, Chiou WF. Comparison of pro-inflammatory cytokines among patients with bipolar disorder, unipolar depression and normal controls. Bipolar Disorders 2015 May;17(3):269-77.

360.  Chang WP, Liu ME, Chang WC, Yang AC, KuYC,Pai JT, Lin YW, Tsai SJ*. Sleep Apnea and the Subsequent Risk of Breast Cancer in Women: A Nationwide Population-based Cohort Study. Sleep Medicine. 2014;14:262-7.

361.  Chu CS, Lu T, Tsai SJ, Hong CJ, Yeh HL, Yang AC, Liu ME. APOE ɛ4 polymorphism and cognitive deficit among the very old Chinese veteran men without dementia. Neurosci Lett 2014;576C:17-21.

362.  Cheng CY, Huang CC, Liu ME, Liou YJ, Wu JC, Tsai SJ, Lin CP, Hong CJ. The association of RAB18 gene polymorphism (rs3765133) with cerebellar volume in healthy adults. Cerebellum 2014;13(5):616-22.

363. Bai YM, Su TP, Tsai SJ, Chiou WF, Li CT, Tu PC, Chen MH. Comparison of inflammatory cytokine levels among type I/type II and manic/hypomanic/euthymic/depressive states of bipolar disorder. Journal of Affective Disorders 2014;166:187–192.

364.  Chang MH, Tsai SJ*. Capgras Syndrome as an Initial Manifestation in a Patient with Neurosyphilis. Journal of Neuropsychiatry and Clinical Neurosciences 2015;27(1):e73.

365.  Tzang ZF, Yang AC, Yeh HL, Liu ME, Tsai SJ*. Association of depression and loneliness with specific cognitive performance in non-demented elderly males. Medical Science Monitor 2015;21:100-4.

366.  Chou PS, Kuo CN, Hung KS, Chang WC, Liao YC, Chi YC, Chou WP, Tsai SJ, Liu ME, Lai CL, Chou YH, Chang WP. Osteoporosis and the Risk of Symptomatic Nephrolithiasis: A Population-Based 5-Year Follow-Up Study in Taiwan. Calcif Tissue Int 2014;95(4):317-22..

367.  Lan WH, Bai YM, Hsu JW, Huang KL, Su TP, Li CT, Yang AC, Lin WC, Chang WH, Chen TJ, Tsai SJ, Chen MH*. Comorbidity of ADHD and suicide attempts among adolescents and young adults with bipolar disorder: A nationwide longitudinal study. J Affect Disord 2015;176C:171-175.

368.  Wang SL, Chang CH, Hu LY, Tsai SJ, Yang AC, You ZH. Risk of Developing Depressive Disorders following Rheumatoid Arthritis: A Nationwide Population-Based Study. PLoS One 2014;9:e107791.

369.  Shen CC, Yang AC, hung JH, Hu LY, Tsai SJ*. Nationwide Population-based Retrospective Cohort Study of the Risk of Uterine, Ovarian and Breast Cancer in Women with Polycystic Ovary Syndrome. The Oncologist 2015;20(1):45-9.

370. Tsai SJ*. Transcranial focused ultrasound as a possible treatment for major depression. Medical Hypotheses 2015;84(4):381-3.

371.  Yang AC*, Hong CJ, Liou YJ, Huang KL, Huang CC, Liu ME, Lo MT, Huang N, Peng CK, Lin CP, Tsai SJ. Decreased Resting-State Brain Activity Complexity in Schizophrenia Characterized by Both Increased Regularity and Randomness. Human Brain Mapping 2015;36(6):2174-86.

372.  Cheng CM, Tsai SJ*. Persistent hiccups associated with switching from paliperidone to amisulpride: a case report. Psychiatry and Clinical Neurosciences 2015;69(6):383.

373.  Cheng CM, Wu YH, Tsai SJ, Bai YM, Hsu JW, Huang KL, Su TP, Li CT, Tsai CF, Yang AC, Lin WC, Pan TL, Chang WH, Chen TJ, Chen MH. Risk of developing Parkinson's disease among patients with asthma: a nationwide longitudinal study. Allergy 2015;70(12):1605-12.

374.  Chen MH, Pan TL, Li CT, Lin WC, Chen YS, Lee YC, Tsai SJ, Hsu JW, Huang KL, Tsai CF, Chang WH, Chen TJ, Su TP, Bai YM. Risk of stroke among patients with post-traumatic stress disorder: nationwide longitudinal study. Br J Psychiatry 2015;206(4):302-7.

375.  Lin E, Tsai SJ*. Pharmacogenetics in methadone therapy. Current Pharmacogenomics and Personalized Medicine 2014:12(4): 199 - 208.

376.  Cheng CY, Wu JC, Tsai JW, Nian FS, Wu PC, Kao LS, Fann MJ, Tsai SJ, Liou YJ, Tai CY, Hong CJ. ENU mutagenesis identifies mice modeling Warburg Micro syndrome with sensory axon degeneration caused by a deletion in Rab18. Exp Neurol 2015;267:143-151.

377.  Shen CC, Yang AC, Kuo BI, Tsai SJ*. Risk of Psychiatric Disorders Following Primary Sjögren Syndrome: A Nationwide Population-based Retrospective Cohort Study. J Rheumatol 2015 Jul;42(7):1203-8.

378.  Biernacka JM, Sangkuhl K, Jenkins G, Whaley RM, Barman P, Batzler A, Altman RB, Arolt V, Brockmöller J, Chen CH, Domschke K, Hall-Flavin DK, Hong CJ, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou YJ, Mushiroda T, Nonen S, Skime MK, Wang L, Baune BT, Kato M, Liu YL, Praphanphoj V, Stingl JC, Tsai SJ, Kubo M, Klein TE, Weinshilboum R. The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response. Transl Psychiatry. 2015 Apr 21;5:e553.

379.  Tsai SJ*. Is riluzole a potential therapy for Rett Syndrome? Medical Hypotheses 2015;85(1):76-8.

380. Cheng CM, Hsu JW, Huang KL, Bai YM, Su TP, Li CT, Yang AC, Chang WH, Chen TJ, Tsai SJ, Chen MH. Risk of developing major depressive disorder and anxiety disorders among adolescents and adults with atopic dermatitis: A nationwide longitudinal study. J Affect Disord 2015;178:60-65.

381.  You ZH, Perng CL, Hu LY, Lu T, Chen PM, Yang AC, Tsai SJ, Huang YS, Chen HJ. Risk of psychiatric disorders following gastroesophageal reflux disease: A nationwide population-based cohort study. Eur J Intern Med 2015;26(7):534-9.

382. Chang MH, Hsu JW, Huang KL, Su TP, Bai YM, Li CT, Yang AC, Chang WH, Chen TJ, Tsai SJ, Chen MH. Bidirectional association between depression and fibromyalgia syndrome: A nationwide longitudinal study. J Pain 2015;16(9):895-902.

383.  Lee YT, Hu LY, Shen CC, Huang MW, Tsai SJ, Yang AC, Hu CK, Perng CL, Huang YS, Hung JH. Risk of Psychiatric Disorders following Irritable Bowel Syndrome: A Nationwide Population-Based Cohort Study. PLoS One 2015;10(7):e0133283.

384.  Lin E, Tsai SJ*. Genome-wide microarray analysis of gene expression profiling in major depression and antidepressant therapy. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2016;64:334-40.

385.  Tsai WT, Tsai SJ*, Yang AC. Cyclic Cushing’s syndrome mimicking bipolar disorder. Psychiatry and Clinical Neurosciences 2016;70(1):71.

386.  Chen LC, Hsu JW, Huang KL, Bai YM, Su TP, Li CT, Yang AC, Chang WH, Chen TJ, Tsai SJ, Chen MH. Risk of developing major depression and anxiety disorders among women with endometriosis: A longitudinal follow-up study. J Affect Disord 2016;190:282-5..

387.  Lan CC, Tsai SJ, Huang CC, Wang YH, Chen TR, Yeh HL, Liu ME, Lin CP, Yang AC. Functional connectivity density mapping of depressive symptoms and loneliness in non-demented elderly male. Front Aging Neurosci 2016;7:251.

388.  Shen CC, Hu LY, Yang AC, Kuo BI, Chiang YY, Tsai SJ*. Risk of Psychiatric Disorders following Ankylosing Spondylitis: A Nationwide Population-based Retrospective Cohort Study. J Rheumatol 2016;43(3):625-31..

389. Shen CC, Yang AC, Hung JH, Hu LY, Chiang YY, Tsai SJ*. Risk of psychiatric disorders following pelvic inflammatory disease: a nationwide population-based retrospective cohort study. J Psychosom Obstet Gynaecol 2016;37(1):6-11.

390. Chen MH, Tsai SJ*. Treatment-resistant panic disorder: Clinical significance, concept and management. Prog Neuropsychopharmacol Biol Psychiatry 2016;70:219-26..

391.  Tseng CC, Hu LY, Liu ME, Yang AC, Shen CC, Tsai SJ*. Risk of depressive disorders following sudden sensorineural hearing loss: A nationwide population-based retrospective cohort study. J Affect Disord 2016;197:94-9.

392.  Huang CC, Liu ME, Kao HW, Chou KH, Yang AC, Wang YH, Chen TR, Tsai SJ*, Lin CP*. Effect of Alzheimer's Disease Risk Variant rs3824968 at SORL1 on Regional Gray Matter Volume and Age-Related Interaction in Adult Lifespan. Sci Rep. 2016;6:23362.

393.  Chen MH, Lan WH, Hsu JW, Huang KL, Su TP, Li CT, Lin WC, Tsai CF, Tsai SJ, Lee YC, Chen YS, Pan TL, Chang WH, Chen TJ, Bai YM. Risk of Developing Type 2 Diabetes in Adolescents and Young Adults With Autism Spectrum Disorder: A Nationwide Longitudinal Study. Diabetes Care 2016;39(5):788-93.

394. Chen MH, Lan WH, Bai YM, Huang KL, Su TP, Tsai SJ, Li CT, Lin WC, Chang WH, Pan TL, Chen TJ, Hsu JW. Influence of Relative Age on Diagnosis and Treatment of Attention-Deficit Hyperactivity Disorder in Taiwanese Children. J Pediatr. 2016;172:162-167.

395.  Bai YM*, Li CT, Tsai SJ, Tu PC, Chen MH, Su TP. Metabolic syndrome and adverse clinical outcomes in patients with bipolar disorder. BMC Psychiatry 2016;16(1):448.

396.  Yang AC*, Tsai SJ, Liu ME, Huang CC, Lin CP. The association of aging with white matter integrity and functional connectivity hubs. Front Aging Neurosci 2016;8:143.

397.  Lin E, Kuo PH, Liu YL, Yang AC, Kao CF, Tsai SJ*. Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population. Scientific Reports 2016;6:36830.

398.  Lin PH, Tsai SJ, Huang CW, Mu-En L, Hsu SW, Lee CC, Chen NC, Chang YT, Lan MY, Chang CC. Dose-dependent genotype effects of BDNF Val66Met polymorphism on default mode network in early stage Alzheimer's disease. Oncotarget 2016;7:54200-54214.

399.  Wang TY, Wei HT, Liou YJ, Su TP, Bai YM, Tsai SJ, Yang AC, Chen TJ, Tsai CF, Chen MH. Risk for developing dementia among patients with posttraumatic stress disorder: A nationwide longitudinal study. J Affect Disord 2016;205:306-310.

400.  Tu YA, Chen MH, Tsai CF, Su TP, Bai YM, Li CT, Lin WC, Liu ME, Pan TL, Chen TJ, Tsai SJ*. Geriatric suicide attempt and risk of subsequent dementia: a nationwide longitudinal follow-up study in Taiwan. American Journal of Geriatric Psychiatry 2016;16:1211-8.

401. Chen MH, Pan TL, Hsu JW, Huang KL, Su TP, Li CT, Lin WC, Tsai SJ, Chang WH, Chen TJ, Bai YM. Attention-deficit hyperactivity disorder comorbidity and antidepressant resistance among patients with major depression: A nationwide longitudinal study. Eur Neuropsychopharmacol 2016;26(11):1760-1767.

402.  Lee CY, Chen MH, Jeng MJ, Hsu JW, Tsai SJ, Bai YM, Hung GY, Yen HJ, Chen TJ, Su TP. Longitudinal association between early atopic dermatitis and subsequent attention-deficit or autistic disorder: A population-based case-control study. Medicine (Baltimore). 2016 Sep;95(39):e5005.

403.  Cheng W, Rolls ET, Qiu J, Liu W, Tang Y, Huang CC, Wang X, Zhang J, Lin W, Zheng L, Pu J, Tsai SJ, Yang AC, Lin CP, Wang F, Xie P, Feng J* Medial reward and lateral non-reward orbitofrontal cortex circuits change in opposite directions in depression. Brain 2016;139(Pt 12):3296-3309.

404. Shen CC, Hu LY, Yang AC, Chiang YY, Hung JH, Tsai SJ*. Risk of uterine, ovarian and breast cancer following pelvic inflammatory disease: a nationwide population-based retrospective cohort study. BMC Cancer 2016;16(1):839.

405.  Shen CC, Hu LY, Tsai SJ, Yang AC, Hu YH*. Risk stratification for the early diagnosis of borderline personality disorder Using Psychiatric Comorbidities. Early Intervention in Psychiatry 2017;17(1):8.

406.  Lin WC, Shen CC, Tsai SJ, Yang AC*. Increased risk of myofascial pain syndrome among patients with insomnia. Pain Medicine 2017;18(8):1557-1565.

407.  Tsai SJ*. Therapeutic potential of transcranial focused ultrasound for Rett syndrome. Med Sci Monit 2016;22:4026-4029.

408.  Tsai SJ*. Role of neurotrophic factors in attention deficit hyperactivity disorder. Cytokine and Growth Factor Reviews 2017;34:35-41.

409.  Lin WC, Hu LY, Tsai SJ, Yang AC, Shen CC. Depression and the risk of vascular dementia: a population-based retrospective cohort study. Int J Geriatr Psychiatry 2017;32(5):556-563.

410.  Huang CW, Hsu SW, Tsai SJ, Chen NC, Liu ME, Lee CC, Huang SH, Chang WN, Chang YT, Tsai WC, Chang CC* Genetic effect of interleukin-1 beta (C-511T) polymorphism on the structural covariance network and white matter integrity in Alzheimer's disease. J Neuroinflammation 2017;14(1):12.

411.  Lin E, Tsai SJ*, Kuo PH, Liu YL, Yang AC, Kao CF. Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. Oncotarget 2017;8(15):24077-87.

412.  Lin E, Tsai SJ (co-first author), Kuo PH, Liu YL, Yang AC, Kao CF, Yang CH*. The ADAMTS9 gene is associated with cognitive aging in the elderly in a Taiwanese population. Plos One 2017;12(2):e0172440.

413.  Lin E, Tsai SJ (co-first author), Kuo PH, Liu YL, Yang AC, Kao CF, Yang CH* The rs1277306 variant of the REST gene confers susceptibility to cognitive aging in an elderly Taiwanese population. Dement Geriatr Cogn Disord 2017;43(3-4):119-127.

414.  Lin E, Kuo PH, Liu YL, Yang AC, Kao CF, Tsai SJ*. Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population. Oncotarget 2017;8(15): 24088-98.

415. Lin E, Kuo PH, Liu YL, Yang AC, Kao CF, Tsai SJ*. Effects of circadian clock genes and health-related behavior on metabolic syndrome in a Taiwanese population: evidence from association and interaction analysis. Plos One 2017;12(3):e0173861.

416.  Chen YH, Wei HT, Bai YM, Hsu JW, Huang KL, Su TP, Li CT, Lin WC, Wu YH, Pan TL, Chen TJ, Tsai SJ, Chen MH*. Risk of epilepsy in Individuals with posttraumatic stress disorder: a nationwide longitudinal study. Psychosom Med 2017;79(6):664-9.

417.  Chan YE, Bai YM, Hsu JW, Huang KL, Su TP, Li CT, Lin WC, Pan TL, Chen TJ, Tsai SJ, Chen MH*. Post-traumatic stress disorder and risk of Parkinson's disease: a nationwide longitudinal study. Am J Geriatr Psychiatry 2017;25(8):917-923..

418.  Tseng CC, Hu LY, Liu ME, Yang AC, Shen CC*, Tsai SJ*. Bidirectional association between Bell’s palsy and anxiety disorders: A nationwide population-based retrospective cohort study. Journal of Affective Disorders 2017;215:269-73.

419.  Chang YT, Hsu SW, Tsai SJ, Chang YT, Huang CW, Liu ME, Chen NC, Chang WN, Hsu JL, Lee CC, Chang CC*. Genetic effect of MTHFR C677T polymorphism on the structural covariance network and white-matter integrity in Alzheimer's disease. Hum Brain Mapp 2017;38:3039-51.

420.  Tsao PC, Lee YS, Jeng MJ, Hsu JW, Huang KL, Tsai SJ, Chen MH, Soong WJ, Kou YR. Additive effect of congenital heart disease and early developmental disorders on attention-deficit/hyperactivity disorder and autism spectrum disorder: a nationwide population-based longitudinal study. Eur Child Adolesc Psychiatry 2017;26(11):1351-9.

421.  Chen MH, Hsu JW, Bai YM, Su TP, Li CT, Lin WC, Tsai SJ, Chang WH, Chen TJ, Huang KL. Risk of stroke among patients with borderline personality disorder: A nationwide longitudinal study. J Affect Disord 2017;219:80-5.

422. Lin E, Tsai SJ*. Multi-omics and machine learning applications in precision medicine. Current Pharmacogenomics and Personalized Medicine 2017;15:97-104.

423.  Chen LC, Yang AC, Su TP, Bai YM, Li CT, Chang WH, Chen TJ, Tsai SJ, Chen MH. Symptomatic menopausal transition and subsequent bipolar disorder among midlife women with major depression: a nationwide longitudinal study. Arch Womens Ment Health 2017;20:463-8.

424.  Tsai SJ*. Effects of interleukin-1beta polymorphisms on brain function and behavior in healthy and psychiatric disease conditions. Cytokine and Growth Factor Reviews 2017;37:89-97.

425.  Lin E, Yang AC, Tsai SJ*. Association between metabolic syndrome and cognitive function in old adults in a Taiwanese population. Taiwanese Journal of Psychiatry 2017;31:232-40.

426.  Yang AC, Tsai SJ*. New targets for schizophrenia treatment beyond the dopamine hypothesis. International Journal of Molecular Sciences 2017;18: E1689.

427.  Chang CC, Tsai SJ, Chen NC, Huang CW, Hsu SW, Chang YT, Liu ME, Chang WN, Tsai WC, Lee CC. Catechol-O-methyltransferase Val158Met polymorphism on striatum structural covariance networks in Alzheimer's disease. Molecular Neurobiology (in Press).

428.  Wang MYH, Tang CH, Tsai SJ, Liu CJ, Wu CS. Hepatitis B and C in Taiwanese patients with schizophrenia: a nationwide, population-based study on prevalence, and healthcare utilization. Journal of Psychology and Psychiatry 2107;1:1-6.

429.  Tsai SJ*. Role of Tissue-type Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Psychological Stress and Depression. Oncotarget 2017;8(68):113258-68.

430. Lin E, Kuo PH, Liu YL, Yang AC, Tsai SJ*. Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population. Oncotarget 2017; 8(55):93349-59.

431.  Chang CC, Chang YT, Huang CW, Tsai SJ, Hsu SW, Huang SH, Lee CC, Chang WN, Lui CC, Lien CY. Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer's disease. Alzheimers Res Ther 2018;10(1):17.

432. Guo S, Huang CC, Zhao W, Yang AC, Lin CP, Nichols T, Tsai SJ*. Combining multi-modality data for searching biomarkers in schizophrenia. PLoS One 2018;13(2):e0191202.

432.  Huang WS, Bai YM, Hsu JW, Huang KL, Tsai CF, Su TP, Li CT, Lin WC, Tsai SJ, Pan TL, Chen TJ, Chen MH. Use of proton pump inhibitors and risk of major depressive disorder: A nationwide population-based study. Psychother Psychosom 2018;87:62-4.

433. Chen MH, Hsu JW, Huang KL, Bai YM, Ko NY, Su TP, Li CT, Lin WC, Tsai SJ, Pan TL, Chang WH, Chen TJ. Sexually transmitted infection among adolescents and young adults with attention-deficit/hyperactivity disorder: A nationwide longitudinal study. J Am Acad Child Adolesc Psychiatry 2018;57:48-53.

434. Jeng JS, Li CT, Chen MH, Lin WC, Bai YM, Tsai SJ, Su TP, Chang WH, Sung YJ. Repeated low-grade infections predict antidepressant-resistant depression: A nationwide population-based cohort study. J Clin Psychiatry 2017;79(1). pii: 17m11540.

435.  Cheng CM, Chang WH, Chen MH, Tsai CF, Su TP, Li CT, Tsai SJ, Hsu JW, Huang KL, Lin WC, Chen TJ, Bai YM. Co-aggregation of major psychiatric disorders in individuals with first-degree relatives with schizophrenia: a nationwide population-based study. Mol Psychiatry. 2017 (in press).

436.  Lin E, Kuo PH, Liu YL, Yang AC, Tsai SJ*. Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population. Sci Rep 2017;7(1):13589.

437. Rolls ET, Cheng W, Gilson M, Qiu J, Hu Z, Ruan H, Li Y, Huang CC, Yang AC, Tsai SJ, Zhang X, Zhuang K, Lin CP, Deco G, Xie P, Feng J. Effective Connectivity in Depression. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Feb;3(2):187-197.

438. Huang KL, Wei HT, Hsu JW, Bai YM, Su TP, Li CT, Lin WC, Tsai SJ, Chang WH, Chen TJ, Chen MH. Risk of suicide attempts in adolescents and young adults with attention-deficit hyperactivity disorder: a nationwide longitudinal study. Br J Psychiatry. 2018 Mar 4:1-5. doi: 10.1192/bjp.2018.8. [Epub ahead of print]

439. Chang CC, Chang YT, Huang CW, Tsai SJ, Hsu SW, Huang SH, Lee CC, Chang WN, Lui CC, Lien CY. Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer's disease. Alzheimers Res Ther. 2018 Feb 8;10(1):17. doi: 10.1186/s13195-018-0344-4.

440. Guo S, Huang CC, Zhao W, Yang AC, Lin CP, Nichols T, Tsai SJ*. Combining multi-modality data for searching biomarkers in schizophrenia. PLoS One. 2018 Feb 1;13(2):e0191202.

441.  Huang WS, Bai YM, Hsu JW, Huang KL, Tsai CF, Su TP, Li CT, Lin WC, Tsai SJ, Pan TL, Chen TJ, Chen MH. Use of Proton Pump Inhibitors and Risk of Major Depressive Disorder: A Nationwide Population-Based Study. Psychother Psychosom. 2018;87(1):62-64.

442.  Huang CC, Yang AC, Chou KH, Liu ME, Fang SC, CC, Tsai SJ*, Lin CP*. Nonlinear pattern of the emergence of white matter hyperintensity in healthy Han Chinese: an adult lifespan study. Neurobiology of Aging 2018 (in press).

 

 

 

Book Chapters:

1. Tsai SJ, Lee TW. Schizophrenia, suicide and the role of serotonin. In Pompili M, et al., ed. Suicide in Schizophrenia. Nova Science Publishers, Inc. (2007).

2. Wang PN, Tsai SJ, Liu HC. Neuropsychological Manifestations in Preclinical Alzheimer’s Disease. In Columbus F, ed. Focus on Alzheimer’s Disease Research. Nova Science Publishers, Inc. (2007).

3. Lin E, Tsai SJ*. Genetics and Suicide. In Philippe Courtet, ed. Understanding Suicide From Diagnosis to Personalized Treatment. Springer Publishers, Inc. (2016).

4. Lin E, Tsai SJ*. Machine learning and predictive algorithms for personalized medicine: from physiology to treatment. In: Turnbull A, editor. Personalized Medicine. New York: Nova Science Publisher, Inc. (2016).

5. Lin E, Tsai SJ*. Diagnostic prediction based on gene expression profiles and artificial neural networks. In Hemant J Purohit, ed. Soft computing in biological sciences. Springer Publishers, Inc. (2017).

6. Lin E, Tsai SJ*. Gene-Environment Interactions and Role of Epigenetics in Depression. In Yong-Ku Kim, ed. Understanding Depression. Springer Publishers, Inc. (2018).

7. Chen MH, Tsai SJ*. Treatment resistance in panic disorder. In Yong-Ku Kim, ed. Treatment Resistance in Psychiatry. Springer Publishers, Inc. (2017).